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Gene : sqh D. melanogaster
DB identifier  ? FBgn0003514 Secondary Identifier  ? CG3595
Name  ? spaghetti squash Source  FlyBase
  • synonyms:
  • MyosinII,
  • Myosin LC,
  • Myo-II,
  • Myosin-II,
  • Myosin Regulatory Light Chain,
  • Spaghetti-Squash,
  • Myosin light chain,
  • RMLC,
  • spg,
  • squ,
  • myosin-II light chain,
  • Spaghetti Squash,
  • regulatory light chain,
  • regulatory light chain of nonmuscle myosin II,
  • MRLC,
  • non-muscle Myosin II,
  • FBan0003595,
  • phospho-Myosin light chain 2,
  • regulatory light chain of Myosin II,
  • MLRC,
  • RLC,
  • ssq,
  • Myosin II,
  • Myo II,
  • Squh,
  • NMM,
  • Myo,
  • FBgn0003514,
  • MLC,
  • Myosin,
  • regulatory light chain of nonmuscle myosin-II,
  • Sqh,
  • myosin 2,
  • MyoII,
  • light chain of nonmuscle Myosin II,
  • Myo-II regulatory light chain,
  • Squash,
  • Myosin II regulatory light chain,
  • non-muscle myosin II regulatory light chain,
  • CG3595,
  • nonmuscle myosin II,
  • nonmuscle myosin II regulatory light chain,
  • MyoII regulatory light chain,
  • DmMRLC_C,
  • type II myosin regulatory light chain,
  • sgh
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42 Alleles

DB identifier Symbol Allele Class Organism
FBal0263515 sqh[DD.Scer\UAS]   Drosophila melanogaster
FBal0241435 sqh[NIG.3595R]   Drosophila melanogaster
FBal0243290 sqh[+tCH322-130G10]   Drosophila melanogaster
FBal0280205 sqh[Ubi-p63E.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0280206 sqh[AA.Ubi-p63E.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0280207 sqh[Scer\UAS.P\T.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0267530 sqh[T20E.S21E.Scer\UAS]   Drosophila melanogaster
FBal0280208 sqh[AA.Scer\UAS.P\T.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0258457 sqh[T:Disc\RFP-mCherry]   Drosophila melanogaster
FBal0245421 sqh[JF01103]   Drosophila melanogaster
FBal0257510 sqh[HMS00830]   Drosophila melanogaster
FBal0158608 sqh[EY09875]   Drosophila melanogaster
FBal0267793 sqh[Scer\UAS.T:Avic\GFP]   Drosophila melanogaster
FBal0259528 sqh[KK107557]   Drosophila melanogaster
FBal0266155 sqh[Scer\UAS.cDa]   Drosophila melanogaster
FBal0266156 sqh[T20A.S21A.Scer\UAS]   Drosophila melanogaster
FBal0266157 sqh[Scer\UAS.cMa]   Drosophila melanogaster
FBal0016066 sqh[1] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0050556 sqh[2] loss of function allele Drosophila melanogaster
FBal0086321 sqh[Gp6]   Drosophila melanogaster
FBal0129034 sqh[PL91]   Drosophila melanogaster
FBal0278575 sqh[GL00663]   Drosophila melanogaster
FBal0246103 sqh[E20E21.Scer\UAS.cCa]   Drosophila melanogaster
FBal0035706 sqh[+t3.0]   Drosophila melanogaster
FBal0050557 sqh[hs.PE]   Drosophila melanogaster
FBal0122886 sqh[E20.E21]   Drosophila melanogaster
FBal0122887 sqh[A20.E21]   Drosophila melanogaster
FBal0177672 sqh[5XA]   Drosophila melanogaster
FBal0146778 sqh[dsRNA.250-1890]   Drosophila melanogaster
FBal0035707 sqh[AX3] amorphic allele - genetic evidence, loss of function allele Drosophila melanogaster

229 Clones

Secondary Identifier DB identifier
UUGC0866 FBcl0004807
AT27429 FBcl0009019
EC39824 FBcl0068903
EP10358 FBcl0084045
EK090446 FBcl0086424
EK258807 FBcl0086634
EK120943 FBcl0086852
EK087624 FBcl0086862
EK222934 FBcl0086868
EK133602 FBcl0086876
EK098305 FBcl0086880
EK044043 FBcl0086938
EK203116 FBcl0086960
EK087620 FBcl0087160
EK152139 FBcl0087170
EK237712 FBcl0087176
EK307422 FBcl0087200
EK184226 FBcl0087206
EK216455 FBcl0087234
EK042851 FBcl0087252
EK089801 FBcl0087310
EK208651 FBcl0087372
EK189001 FBcl0087378
EK292804 FBcl0087384
EK170143 FBcl0087394
EK054622 FBcl0087402
EK187252 FBcl0087414
EK183219 FBcl0087456
EK293003 FBcl0087464
EN14655 FBcl0097847

6 Exons

DB identifier Symbol
FBgn0003514:6 sqh:6
FBgn0003514:2 sqh:2
FBgn0003514:1 sqh:1
FBgn0003514:3 sqh:3
FBgn0003514:4 sqh:4
FBgn0003514:5 sqh:5

4 Transcripts

DB identifier Gene
FBtr0070877 sqh
FBtr0339502 sqh
FBtr0339503 sqh
FBtr0339504 sqh

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0070877-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0339502-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0339503-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0339504-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0070877-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0339502-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0339503-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0339504-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

2 Cross References

Identifier
Source . Name
Subject . Primary Identifier
31554 NCBI Entrez Gene identifiers FBgn0003514
58046 BioGRID FBgn0003514

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier
Submission . Title
Cell Line . Name
Developmental Stage . Name 		Score
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 2958.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 3368.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 2826.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 4325.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 3728.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 4800.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 4142.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 3280.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 3648.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 3732.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 3782.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 2323.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 5012.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 4515.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 3321.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 2787.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 4172.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 4045.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 5525.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 2766.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2628.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2279.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 3026.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2265.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2848.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1411.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1610.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2350.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1931.0
FBgn0003514 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1927.0

5 Introns

DB identifier
Organism . Name
intron_FBgn0003514:6_FBgn0003514:2 Drosophila melanogaster
intron_FBgn0003514:2_FBgn0003514:1 Drosophila melanogaster
intron_FBgn0003514:3_FBgn0003514:2 Drosophila melanogaster
intron_FBgn0003514:4_FBgn0003514:2 Drosophila melanogaster
intron_FBgn0003514:5_FBgn0003514:2 Drosophila melanogaster

25 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage sqh none -0.550659168   19067489
Lipid storage sqh none 0.094681504   19067489
Lipid storage sqh none -0.051340138   19067489
Lipid storage sqh none 0.048610458   19067489
Cytokinesis sqh Multi-nucleate cells np   15380073
Cytokinesis regulation sqh Binucleate cells weak   15547975
Cell size and cell-cycle regulation (1) sqh none sp   16496002
Muscle morphogenesis and function (1) sqh Lethal np   20220848
Muscle morphogenesis and function (1) sqh none np   20220848
Heat nociception (1) sqh none -1.17   21074052
Heart development and function (1) sqh none 1   20371351
Heart development and function (2) sqh Decreased viability 3.63   20371351
Serratia marcescens infection (1) sqh none -0.309734513274336   19520911
Serratia marcescens infection (1) sqh none 0.5   19520911
Notch pathway regulation (4) sqh Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) sqh Completely lethal (pupal) sp   19363474
Notch induced transcription sqh Downregulation of Notch pathway after Notch stimulation -2.8868 N(delta)ecn Notch stimulation 20959007
Notch induced transcription sqh none -0.12006 N(delta)ecn Notch stimulation 20959007
Notch induced transcription sqh none -1.2336 without Notch stimulation 20959007
Muscle assembly and maintenance sqh Muscles spread, myosin filaments striated, actin filaments lack striation np   18359903
Self-renewal and differentiation in neural stem cells sqh GFP aggregates number, GFP aggregates size, neuroblast abnormally large cell size, neuroblast larger cell size, neuroblast cell shape, ganglion mother cell shorter lineages, extremely increased neuroblast cell size without neuroblast loss, neuroblast unde sp   21549331
Notch pathway regulation (3) sqh Upregulation of Notch pathway np   20493818
Adiposity regulation (1) sqh none -0.144   20074523
Hippo pathway regulation sqh none -0.84   23263283
Glycosylation regulation (1) sqh none sp   21203496

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