Genomics
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6 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0122297 | RpS23[EP638] | Drosophila melanogaster | |
| FBal0148149 | RpS23[KG07144] | Drosophila melanogaster | |
| FBal0148148 | RpS23[dsRNA.cLa] | Drosophila melanogaster | |
| FBal0287251 | RpS23[Scer\UAS.ORF] | Drosophila melanogaster | |
| FBal0208376 | RpS23[GD12525] | Drosophila melanogaster | |
| FBal0208377 | RpS23[GD17535] | Drosophila melanogaster |
543 Clones
5 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0033912:5 | RpS23:5 |
| FBgn0033912:3 | RpS23:3 |
| FBgn0033912:1 | RpS23:1 |
| FBgn0033912:2 | RpS23:2 |
| FBgn0033912:4 | RpS23:4 |
4 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0339970-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0087575-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0339970-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0087575-3-prime-utr | Drosophila melanogaster |
Other
52 Pathways
- GTP hydrolysis and joining of the 60S ribosomal subunit,
- Peptide chain elongation,
- Transport of Mature mRNA derived from an Intron-Containing Transcript,
- SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs,
- Post-Elongation Processing of the Transcript,
- Processing of Intronless Pre-mRNAs,
- RNA Polymerase II Transcription Initiation,
- Post-Elongation Processing of Intronless pre-mRNA,
- RNA Polymerase II Transcription Initiation And Promoter Clearance,
- Nonsense-Mediated Decay,
- Eukaryotic Translation Elongation,
- Nonsense Mediated Decay Independent of the Exon Junction Complex,
- RNA Polymerase II Promoter Escape,
- SLBP independent Processing of Histone Pre-mRNAs,
- Nonsense Mediated Decay Enhanced by the Exon Junction Complex,
- Formation of a pool of free 40S subunits,
- Eukaryotic Translation Initiation,
- RNA Polymerase II Transcription,
- Transcription,
- Transport of Mature mRNA Derived from an Intronless Transcript,
- Metabolism of RNA,
- Elongation arrest and recovery,
- Processing of Capped Intronless Pre-mRNA,
- Cleavage of Growing Transcript in the Termination Region,
- Formation of the ternary complex, and subsequently, the 43S complex,
- Translation,
- mRNA Capping,
- Metabolism of proteins,
- Formation of the Early Elongation Complex,
- Ribosomal scanning and start codon recognition,
- SRP-dependent cotranslational protein targeting to membrane,
- Transport of the SLBP Dependant Mature mRNA,
- Transport of Mature mRNAs Derived from Intronless Transcripts,
- L13a-mediated translational silencing of Ceruloplasmin expression,
- Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S,
- Eukaryotic Translation Termination,
- Processing of Capped Intron-Containing Pre-mRNA,
- RNA Polymerase II Pre-transcription Events,
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,
- Gene Expression,
- RNA Polymerase II Transcription Termination,
- Cap-dependent Translation Initiation,
- Recycling of eIF2:GDP,
- 3' -UTR-mediated translational regulation,
- RNA Polymerase II Transcription Elongation,
- Transport of the SLBP independent Mature mRNA,
- Translation initiation complex formation,
- Formation of RNA Pol II elongation complex,
- Metabolism of mRNA,
- Transport of Mature Transcript to Cytoplasm,
- RNA Pol II CTD phosphorylation and interaction with CE,
- mRNA Processing
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 36576 | NCBI Entrez Gene identifiers | FBgn0033912 |
| 62326 | BioGRID | FBgn0033912 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
30 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | RpS23 | Increased lipid droplet area | 4.464360117 | 19067489 | |
| Lipid storage | RpS23 | Increased lipid droplet area | 12.03087488 | 19067489 | |
| ERK signaling | RpS23 | ERK activation reduced | weak | 17086199 | |
| Drosophila C virus infection | RpS23 | Drosophila C virus replication down | np | 17040126 | |
| Hedgehog signaling | RpS23 | Decreased Hedgehog reporter activity | np | 12663920 | |
| Drosophila C virus infection | RpS23 | Drosophila C virus infection reduced | np | 15713840 | |
| Hedgehog signaling | RpS23 | Decreased Hedgehog reporter activity | -2.84 | 16311596 | |
| Constitutive protein secretion and Golgi organization (1) | RpS23 | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
| Cell size and cell-cycle regulation (1) | RpS23 | none | sp | 16496002 | |
| Candida albicans phagocytosis (1) | RpS23 | none | np | 16336044 | |
| Lipid storage | RpS23 | More dispersed droplets | strong (but ribosomal) | 18408709 | |
| Muscle morphogenesis and function (1) | RpS23 | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (1) | RpS23 | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (3) | RpS23 | Fading Z-line | np | 20220848 | |
| Heat nociception (1) | RpS23 | none | -1.17 | 21074052 | |
| Heat nociception (1) | RpS23 | Developmentally lethal | 0 | 21074052 | |
| Heart development and function (1) | RpS23 | Pupal lethal | 0.15 | 20371351 | |
| Heart development and function (1) | RpS23 | Larval lethal | 0 | 20371351 | |
| Heart development and function (1) | RpS23 | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | RpS23 | none | 0.401960784313725 | 19520911 | |
| Notch pathway regulation (4) | RpS23 | Completely lethal (before pupal) | sp | 19363474 | |
| Notch pathway regulation (4) | RpS23 | Completely lethal (before pupal) | sp | 19363474 | |
| PGN-induced dJNK phosphorylation | RpS23 | Increased P-JNK protein expression with PGN | 3.27 | 60 min PGN induction | 19893628 |
| Hh pathway regulation | RpS23 | Downregulation of Hh pathway | -0.290748454271747 | 17903264 | |
| Adiposity regulation (1) | RpS23 | none | 0.155 | 20074523 | |
| RTK-Ras-ERK pathway regulation (1) | RpS23 | none | 0.56 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | RpS23 | Decreased ERK phosphorylation after EGF stimulation | -3.77 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpS23 | Increased ERK phosphorylation after sSpitz and EGF stimulation | 2.07 | 10 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpS23 | Increased ERK phosphorylation after sSpitz and EGF stimulation | 2.23 | 30 minutes sSpitz stimulation | 22028469 |
| Hippo pathway regulation | RpS23 | none | 0.16 | 23263283 |
