Genomics
Gene Ontology Displayer
Homologue Displayer
Mod Mine G Browse Displayer
Overlapping Features Displayer
Regulatory Regions Displayer
96 Alleles
118 Clones
13 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0011766:13 | E2f:13 |
| FBgn0011766:12 | E2f:12 |
| FBgn0011766:9 | E2f:9 |
| FBgn0011766:7 | E2f:7 |
| FBgn0011766:6 | E2f:6 |
| FBgn0011766:4 | E2f:4 |
| FBgn0011766:3 | E2f:3 |
| FBgn0011766:2 | E2f:2 |
| FBgn0011766:11 | E2f:11 |
| FBgn0011766:8 | E2f:8 |
| FBgn0011766:1 | E2f:1 |
| FBgn0011766:10 | E2f:10 |
| FBgn0011766:5 | E2f:5 |
8 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0084117-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0084118-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0084119-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0334678-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0084117-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0084118-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0084119-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0334678-3-prime-utr | Drosophila melanogaster |
Other
18 Pathways
- M/G1 Transition,
- Regulation of DNA replication,
- Inhibition of replication initiation of damaged DNA by RB1/E2F1,
- Cell Cycle, Mitotic,
- Assembly of the pre-replicative complex,
- DNA Replication,
- E2F mediated regulation of DNA replication,
- G1/S-Specific Transcription,
- G2 Phase,
- Cell Cycle,
- Association of licensing factors with the pre-replicative complex,
- Mitotic M-M/G1 phases,
- Mitotic G1-G1/S phases,
- DNA Replication Pre-Initiation,
- Mitotic G2-G2/M phases,
- G0 and Early G1,
- CDC6 association with the ORC:origin complex,
- G1/S Transition
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 42550 | NCBI Entrez Gene identifiers | FBgn0011766 |
| 67516 | BioGRID | FBgn0011766 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
13 Introns
32 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | E2f | none | 1.707395202 | 19067489 | |
| Lipid storage | E2f | none | 0.61371399 | 19067489 | |
| ERK signaling | E2f | ERK activation reduced | strong | 17086199 | |
| Cytokinesis regulation | E2f | Binucleate cells with decreased viability | weak | 15547975 | |
| Intracellular Listeria monocytogenes infection | E2f | Increased GFP protein expression | weak | 16020693 | |
| Innate immunity | E2f | Increased IMD reporter activity | np | 16163390 | |
| Constitutive protein secretion and Golgi organization (1) | E2f | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
| Cell size and cell-cycle regulation (1) | E2f | Increased G1 DNA content, decreased G2 DNA content, increased G1 cell size, increased G2 cell size | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | E2f | none | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | E2f | Increased G1 DNA content, decreased G2 DNA content, increased G1 cell size, increased G2 cell size | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | E2f | none | sp | 16496002 | |
| Cell size and cell-cycle regulation (2) | E2f | none | 1.144 | 16496002 | |
| Cell size and cell-cycle regulation (2) | E2f | none | 1.275 | 16496002 | |
| Cell size and cell-cycle regulation (3) | E2f | none | 424 | 16496002 | |
| Cell size and cell-cycle regulation (3) | E2f | none | 426 | 16496002 | |
| Heart development and function | E2f | Posterior portion assembly defects | np | 14684833 | |
| Dendrite pattern formation | E2f | Increased arborization | np | 16547170 | |
| Mutant human huntingtin aggregation | E2f | Increased mutant human huntingtin aggregation | 1.5 - 2 | 19789644 | |
| Muscle morphogenesis and function (1) | E2f | none | np | 20220848 | |
| Muscle morphogenesis and function (1) | E2f | none | np | 20220848 | |
| Heat nociception (1) | E2f | none | -1.17 | 21074052 | |
| Heat nociception (1) | E2f | none | -1.17 | 21074052 | |
| Heart development and function (1) | E2f | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | E2f | none | 0.905882352941176 | 19520911 | |
| Notch pathway regulation (4) | E2f | Bristle morphology defects, notum malformation migration, notum malformation death | sp | 19363474 | |
| Notch pathway regulation (4) | E2f | Bristle morphology defects, notum malformation migration | sp | 19363474 | |
| Adiposity regulation (1) | E2f | none | 0.016 | 20074523 | |
| RTK-Ras-ERK pathway regulation (1) | E2f | Decreased ERK phosphorylation after EGF stimulation | -2.58 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | E2f | Decreased ERK phosphorylation after EGF stimulation | -2.67 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | E2f | Increased ERK phosphorylation after sSpitz and EGF stimulation | 10.06 | 10 minutes sSpitz stimulation | 22028469 |
