Genomics
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4 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0287401 | RpL31[Scer\UAS.ORF] | Drosophila melanogaster | |
| FBal0287402 | RpL31[Scer\UAS.ORF.T:Ivir\HA1] | Drosophila melanogaster | |
| FBal0208347 | RpL31[GD8622] | Drosophila melanogaster | |
| FBal0235997 | RpL31[KK109038] | Drosophila melanogaster |
333 Clones
5 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0025286:2 | RpL31:2 |
| FBgn0025286:4 | RpL31:4 |
| FBgn0025286:5 | RpL31:5 |
| FBgn0025286:3 | RpL31:3 |
| FBgn0025286:1 | RpL31:1 |
6 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0088526-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0088527-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0088525-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0088526-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0088527-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0088525-3-prime-utr | Drosophila melanogaster |
Other
49 Pathways
- RNA Pol II CTD phosphorylation and interaction with CE,
- Cleavage of Growing Transcript in the Termination Region,
- Nonsense Mediated Decay Independent of the Exon Junction Complex,
- Nonsense-Mediated Decay,
- Gene Expression,
- Processing of Intronless Pre-mRNAs,
- 3' -UTR-mediated translational regulation,
- Transport of Mature Transcript to Cytoplasm,
- Cap-dependent Translation Initiation,
- Transport of the SLBP Dependant Mature mRNA,
- RNA Polymerase II Transcription Termination,
- Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S,
- SLBP independent Processing of Histone Pre-mRNAs,
- Processing of Capped Intronless Pre-mRNA,
- Post-Elongation Processing of Intronless pre-mRNA,
- Translation,
- RNA Polymerase II Promoter Escape,
- RNA Polymerase II Transcription,
- Transport of Mature mRNA Derived from an Intronless Transcript,
- Post-Elongation Processing of the Transcript,
- Transport of Mature mRNAs Derived from Intronless Transcripts,
- Ribosomal scanning and start codon recognition,
- mRNA Capping,
- Eukaryotic Translation Termination,
- Transport of the SLBP independent Mature mRNA,
- Peptide chain elongation,
- Processing of Capped Intron-Containing Pre-mRNA,
- Metabolism of mRNA,
- Transport of Mature mRNA derived from an Intron-Containing Transcript,
- Transcription,
- Eukaryotic Translation Initiation,
- RNA Polymerase II Transcription Initiation And Promoter Clearance,
- RNA Polymerase II Pre-transcription Events,
- Formation of RNA Pol II elongation complex,
- L13a-mediated translational silencing of Ceruloplasmin expression,
- SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs,
- RNA Polymerase II Transcription Elongation,
- Eukaryotic Translation Elongation,
- Nonsense Mediated Decay Enhanced by the Exon Junction Complex,
- RNA Polymerase II Transcription Initiation,
- mRNA Processing,
- Metabolism of RNA,
- Formation of the Early Elongation Complex,
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,
- GTP hydrolysis and joining of the 60S ribosomal subunit,
- SRP-dependent cotranslational protein targeting to membrane,
- Elongation arrest and recovery,
- Formation of a pool of free 40S subunits,
- Metabolism of proteins
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 35988 | NCBI Entrez Gene identifiers | FBgn0025286 |
| 61819 | BioGRID | FBgn0025286 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
33 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | RpL31 | Increased lipid droplet area | 3.211582693 | 19067489 | |
| Lipid storage | RpL31 | Increased lipid droplet area | 5.9242268 | 19067489 | |
| ERK signaling | RpL31 | ERK activation reduced | weak | 17086199 | |
| Drosophila C virus infection | RpL31 | Drosophila C virus replication down | np | 17040126 | |
| Cytokinesis regulation | RpL31 | Binucleate cells | medium | 15547975 | |
| Drosophila C virus infection | RpL31 | Drosophila C virus infection reduced | np | 15713840 | |
| Hedgehog signaling | RpL31 | Decreased Hedgehog reporter activity | -3.92 | 16311596 | |
| Constitutive protein secretion and Golgi organization (1) | RpL31 | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
| Cell size and cell-cycle regulation (1) | RpL31 | Increased G1 DNA content, decreased viability | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | RpL31 | none | sp | 16496002 | |
| Cell size and cell-cycle regulation (2) | RpL31 | Decreased viability | 0.634 | 16496002 | |
| Cell size and cell-cycle regulation (3) | RpL31 | Decreased cell number | 383 | 16496002 | |
| Lipid storage | RpL31 | More dispersed droplets | strong (but ribosomal) | 18408709 | |
| Combinatorial effect with methyl methanesulphonate (2) | RpL31 | none | sp | 19543366 | |
| Heat nociception (1) | RpL31 | Developmentally lethal | 0.07 | 21074052 | |
| Heart development and function (1) | RpL31 | Embryonic lethal or no offspring | 0 | 20371351 | |
| Serratia marcescens infection (1) | RpL31 | none | 1.16071428571428 | 19520911 | |
| Notch pathway regulation (4) | RpL31 | Completely lethal (pupal) | sp | 19363474 | |
| PGN-induced dJNK phosphorylation | RpL31 | Decreased P-JNK protein expression with PGN | -3.57 | 15 min PGN induction | 19893628 |
| Hh pathway regulation | RpL31 | Downregulation of Hh pathway | -0.533375673203387 | 17903264 | |
| Notch pathway regulation (1) | RpL31 | Downregulation of Notch pathway | np | 20493818 | |
| Adiposity regulation (1) | RpL31 | Decreased triglyceride expression | -1 | 20074523 | |
| Adiposity regulation (2) | RpL31 | Lethal or developmental delay | d/l | 20074523 | |
| Adiposity regulation (3) | RpL31 | Lethal or developmental delay | d/l | 20074523 | |
| Adiposity regulation (4) | RpL31 | Lethal or developmental delay | d/l | 20074523 | |
| Adiposity regulation (5) | RpL31 | Lethal or developmental delay | d/l | 20074523 | |
| Blood cell homeostasis regulation (1) | RpL31 | none | np | 20540764 | |
| Blood cell homeostasis regulation (2) | RpL31 | none | np | 20540764 | |
| RTK-Ras-ERK pathway regulation (1) | RpL31 | Decreased ERK phosphorylation after EGF stimulation | -3.71 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | RpL31 | none | -1.42 | 0 minutes EGF stimulation | 22028469 |
