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Gene : Nedd4 D. melanogaster

DB identifier  ? FBgn0259174 Secondary Identifier  ? CG42279
Name  ? Nedd4 Source  FlyBase
  • synonyms:
  • FBan0007555,
  • CG42279,
  • FBgn0036736,
  • FBan0032184,
  • FBgn0259174,
  • dNedd4-1,
  • CG7555,
  • nedd4,
  • DNedd4,
  • CG32184,
  • FBgn0052184

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55 Alleles

DB identifier Symbol Allele Class Organism
FBal0265776 Nedd4[Scer\UAS.Short.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0283867 Nedd4[MI07766]   Drosophila melanogaster
FBal0265777 Nedd4[Scer\UAS.Long.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0265778 Nedd4[S444A.Scer\UAS.Short.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0265779 Nedd4[S39A.S645A.Scer\UAS.Long.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0265780 Nedd4[DeltaNterm.Scer\UAS.Long.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0265781 Nedd4[DeltaMid.Scer\UAS.Long.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0265782 Nedd4[C961A.Scer\UAS.Long.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0182551 Nedd4[DG05310]   Drosophila melanogaster
FBal0182548 Nedd4[GS13178]   Drosophila melanogaster
FBal0182532 Nedd4[c01057]   Drosophila melanogaster
FBal0182531 Nedd4[c01068]   Drosophila melanogaster
FBal0182530 Nedd4[d05280]   Drosophila melanogaster
FBal0245967 Nedd4[JF01860]   Drosophila melanogaster
FBal0182526 Nedd4[f04967]   Drosophila melanogaster
FBal0182527 Nedd4[f03481]   Drosophila melanogaster
FBal0182528 Nedd4[f00732]   Drosophila melanogaster
FBal0182534 Nedd4[c00994]   Drosophila melanogaster
FBal0182533 Nedd4[c01016]   Drosophila melanogaster
FBal0257877 Nedd4[HMS01221]   Drosophila melanogaster
FBal0147733 Nedd4[EY00500]   Drosophila melanogaster
FBal0182543 Nedd4[N121FS]   Drosophila melanogaster
FBal0141636 Nedd4[dsRNA.cMa]   Drosophila melanogaster
FBal0141639 Nedd4[Deltahect.MtnA]   Drosophila melanogaster
FBal0182553 Nedd4[C974FS]   Drosophila melanogaster
FBal0182544 Nedd4[M884I]   Drosophila melanogaster
FBal0182541 Nedd4[N728S]   Drosophila melanogaster
FBal0182552 Nedd4[D730FS]   Drosophila melanogaster
FBal0182540 Nedd4[Q855stop]   Drosophila melanogaster
FBal0182549 Nedd4[G746S]   Drosophila melanogaster

132 Clones

Secondary Identifier DB identifier
DPiM_SD04682 FBcl0740843
AT02728 FBcl0007457
AT04181 FBcl0007713
bs18h02 FBcl0048237
CK00535 FBcl0059103
EK186748 FBcl0070140
EK281149 FBcl0075628
EP05838 FBcl0075775
EP05808 FBcl0075793
EP18411 FBcl0075803
EP16325 FBcl0075889
EK264815 FBcl0075944
EK166314 FBcl0076024
EK179314 FBcl0076108
EK137601 FBcl0076350
EK175510 FBcl0076376
EK086049 FBcl0076534
EK056355 FBcl0076564
EK102126 FBcl0076626
EK154044 FBcl0076700
EK266054 FBcl0077484
EK092018 FBcl0078478
EK093128 FBcl0078552
EK162249 FBcl0079484
EN05715 FBcl0092135
EN09927 FBcl0092137
EN06501 FBcl0092143
EN04529 FBcl0092151
EK041124 FBcl0101654
EK194924 FBcl0101696

30 Exons

DB identifier Symbol
FBgn0259174:3 Nedd4:3
FBgn0259174:10 Nedd4:10
FBgn0259174:17 Nedd4:17
FBgn0259174:19 Nedd4:19
FBgn0259174:20 Nedd4:20
FBgn0259174:1 Nedd4:1
FBgn0259174:2 Nedd4:2
FBgn0259174:16 Nedd4:16
FBgn0259174:18 Nedd4:18
FBgn0259174:4 Nedd4:4
FBgn0259174:5 Nedd4:5
FBgn0259174:6 Nedd4:6
FBgn0259174:7 Nedd4:7
FBgn0259174:8 Nedd4:8
FBgn0259174:9 Nedd4:9
FBgn0259174:12 Nedd4:12
FBgn0259174:13 Nedd4:13
FBgn0259174:14 Nedd4:14
FBgn0259174:22 Nedd4:22
FBgn0259174:23 Nedd4:23
FBgn0259174:24 Nedd4:24
FBgn0259174:25 Nedd4:25
FBgn0259174:26 Nedd4:26
FBgn0259174:27 Nedd4:27
FBgn0259174:28 Nedd4:28
FBgn0259174:29 Nedd4:29
FBgn0259174:30 Nedd4:30
FBgn0259174:11 Nedd4:11
FBgn0259174:15 Nedd4:15
FBgn0259174:21 Nedd4:21

9 Transcripts

DB identifier Gene
FBtr0299645 Nedd4
FBtr0300519 Nedd4
FBtr0299646 Nedd4
FBtr0331843 Nedd4
FBtr0299647 Nedd4
FBtr0300520 Nedd4
FBtr0299648 Nedd4
FBtr0331844 Nedd4
FBtr0299642 Nedd4

18 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0299642-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0299645-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0299646-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0299647-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0299648-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300519-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300520-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0331843-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0331844-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0299642-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0299645-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0299646-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0299647-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0299648-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0300519-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0300520-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0331843-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0331844-3-prime-utr Drosophila melanogaster

Interactions

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Other

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
39958 NCBI Entrez Gene identifiers FBgn0259174
65246 BioGRID FBgn0259174

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 2871.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1619.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 816.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1375.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1276.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1692.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1678.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1673.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 2239.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1583.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2424.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1534.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1175.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1721.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1982.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 2537.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1836.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1357.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 2497.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1479.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2443.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 980.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1830.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1575.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1446.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 6305.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2792.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2034.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1320.0
FBgn0259174 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1631.0

37 Introns

DB identifier
Organism . Name
intron_FBgn0259174:3_FBgn0259174:5 Drosophila melanogaster
intron_FBgn0259174:5_FBgn0259174:6 Drosophila melanogaster
intron_FBgn0259174:6_FBgn0259174:7 Drosophila melanogaster
intron_FBgn0259174:7_FBgn0259174:8 Drosophila melanogaster
intron_FBgn0259174:8_FBgn0259174:10 Drosophila melanogaster
intron_FBgn0259174:10_FBgn0259174:12 Drosophila melanogaster
intron_FBgn0259174:12_FBgn0259174:13 Drosophila melanogaster
intron_FBgn0259174:13_FBgn0259174:14 Drosophila melanogaster
intron_FBgn0259174:14_FBgn0259174:17 Drosophila melanogaster
intron_FBgn0259174:17_FBgn0259174:19 Drosophila melanogaster
intron_FBgn0259174:19_FBgn0259174:20 Drosophila melanogaster
intron_FBgn0259174:20_FBgn0259174:22 Drosophila melanogaster
intron_FBgn0259174:22_FBgn0259174:23 Drosophila melanogaster
intron_FBgn0259174:23_FBgn0259174:24 Drosophila melanogaster
intron_FBgn0259174:24_FBgn0259174:25 Drosophila melanogaster
intron_FBgn0259174:25_FBgn0259174:26 Drosophila melanogaster
intron_FBgn0259174:26_FBgn0259174:27 Drosophila melanogaster
intron_FBgn0259174:27_FBgn0259174:28 Drosophila melanogaster
intron_FBgn0259174:28_FBgn0259174:29 Drosophila melanogaster
intron_FBgn0259174:1_FBgn0259174:2 Drosophila melanogaster
intron_FBgn0259174:2_FBgn0259174:6 Drosophila melanogaster
intron_FBgn0259174:14_FBgn0259174:16 Drosophila melanogaster
intron_FBgn0259174:16_FBgn0259174:22 Drosophila melanogaster
intron_FBgn0259174:17_FBgn0259174:18 Drosophila melanogaster
intron_FBgn0259174:18_FBgn0259174:22 Drosophila melanogaster
intron_FBgn0259174:4_FBgn0259174:5 Drosophila melanogaster
intron_FBgn0259174:8_FBgn0259174:9 Drosophila melanogaster
intron_FBgn0259174:9_FBgn0259174:12 Drosophila melanogaster
intron_FBgn0259174:14_FBgn0259174:22 Drosophila melanogaster
intron_FBgn0259174:18_FBgn0259174:20 Drosophila melanogaster

24 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Nedd4 none 0.000649945   19067489
Lipid storage Nedd4 none 0.243606232   19067489
Lipid storage Nedd4 none 0.391283271   19067489
Lipid storage Nedd4 none 1.911479105   19067489
L. monocytogenes infection Nedd4 Escape pff LLO- strain *   16157870
Cell size and cell-cycle regulation (1) Nedd4 none sp   16496002
Cell size and cell-cycle regulation (1) Nedd4 none sp   16496002
Cell size and cell-cycle regulation (1) Nedd4 none sp   16496002
Endocytosis Nedd4 none np   18057029
Mutant human huntingtin aggregation Nedd4 Increased mutant human huntingtin aggregation 1.5 - 2   19789644
Muscle morphogenesis and function (1) Nedd4 none np   20220848
Heat nociception (1) Nedd4 none -1.17   21074052
Heart development and function (1) Nedd4 none 1   20371351
Serratia marcescens infection (1) Nedd4 none 0.179245283018867   19520911
Notch pathway regulation (4) Nedd4 Notum malformation migration 1   19363474
Adiposity regulation (1) Nedd4 none -0.034   20074523
Blood cell homeostasis regulation (1) Nedd4 none np   20540764
Blood cell homeostasis regulation (2) Nedd4 none np   20540764
Blood cell homeostasis regulation (3) Nedd4 none 0   20540764
Blood cell homeostasis regulation (4) Nedd4 none 0   20540764
Blood cell homeostasis regulation (5) Nedd4 none 0   20540764
Hippo pathway regulation Nedd4 none -0.68   23263283
Hippo pathway regulation Nedd4 none -0.04   23263283
Glycosylation regulation (1) Nedd4 none sp   21203496

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