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Gene : 4EHP D. melanogaster
DB identifier  ? FBgn0053100 Secondary Identifier  ? CG33100
Name  ? eIF4E-Homologous Protein Source  FlyBase
  • synonyms:
  • d4EHP,
  • CT30033,
  • 4EHP,
  • CG10716,
  • eIF4E-8,
  • 4E-HP,
  • FBgn0053100,
  • FBgn0039148,
  • CG33100,
  • FBan0033100
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34 Alleles

DB identifier Symbol Allele Class Organism
FBal0211833 4EHP[CB05417]   Drosophila melanogaster
FBal0188358 4EHP[DG10811]   Drosophila melanogaster
FBal0188349 4EHP[e04418]   Drosophila melanogaster
FBal0188355 4EHP[c05841]   Drosophila melanogaster
FBal0188352 4EHP[d06795]   Drosophila melanogaster
FBal0188347 4EHP[f03038]   Drosophila melanogaster
FBal0188348 4EHP[f02839]   Drosophila melanogaster
FBal0188350 4EHP[e04417]   Drosophila melanogaster
FBal0157014 4EHP[06737]   Drosophila melanogaster
FBal0266357 4EHP[GL01035]   Drosophila melanogaster
FBal0260550 4EHP[MI03197]   Drosophila melanogaster
FBal0188351 4EHP[e01165]   Drosophila melanogaster
FBal0188353 4EHP[c06768]   Drosophila melanogaster
FBal0188354 4EHP[c05943]   Drosophila melanogaster
FBal0188356 4EHP[c02059]   Drosophila melanogaster
FBal0188357 4EHP[c00588]   Drosophila melanogaster
FBal0161555 4EHP[e03164]   Drosophila melanogaster
FBal0161556 4EHP[EY08369]   Drosophila melanogaster
FBal0157012 4EHP[EP3215]   Drosophila melanogaster
FBal0157013 4EHP[10660]   Drosophila melanogaster
FBal0124408 4EHP[BG01713]   Drosophila melanogaster
FBal0192974 4EHP[CP53] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0192975 4EHP[Scer\UAS.P\T.cCa]   Drosophila melanogaster
FBal0192976 4EHP[W85F.Scer\UAS.P\T]   Drosophila melanogaster
FBal0192977 4EHP[W114A.Scer\UAS.P\T]   Drosophila melanogaster
FBal0198588 4EHP[GD7071]   Drosophila melanogaster
FBal0215483 4EHP[05b]   Drosophila melanogaster
FBal0288008 4EHP[C790]   Drosophila melanogaster
FBal0223220 4EHP[5-HA-1159]   Drosophila melanogaster
FBal0223221 4EHP[d02782]   Drosophila melanogaster

140 Clones

Secondary Identifier DB identifier
DPiM_SD07020 FBcl0742012
bs64g04 FBcl0053081
EC00872 FBcl0062347
EP12653 FBcl0075547
EN16911 FBcl0091939
EN14526 FBcl0091945
EN07243 FBcl0091951
EK173816 FBcl0119888
EK298860 FBcl0119896
EK162715 FBcl0119926
EK204814 FBcl0120198
EK056604 FBcl0120208
EK184930 FBcl0120234
EK196635 FBcl0120240
EK056826 FBcl0120254
EK175146 FBcl0120262
EK247443 FBcl0120266
EK153430 FBcl0120270
EK123807 FBcl0120278
EK166102 FBcl0120298
EK236612 FBcl0120304
EK095160 FBcl0120308
EK065318 FBcl0120324
EK048412 FBcl0120330
EK047833 FBcl0120340
EK112759 FBcl0120350
EK106054 FBcl0120392
EK250312 FBcl0120400
EK182906 FBcl0120404
EK276022 FBcl0120448

8 Exons

DB identifier Symbol
FBgn0053100:8 4EHP:8
FBgn0053100:7 4EHP:7
FBgn0053100:3 4EHP:3
FBgn0053100:1 4EHP:1
FBgn0053100:6 4EHP:6
FBgn0053100:5 4EHP:5
FBgn0053100:4 4EHP:4
FBgn0053100:2 4EHP:2

4 Transcripts

DB identifier Gene
FBtr0300475 4EHP
FBtr0303160 4EHP
FBtr0084587 4EHP
FBtr0303159 4EHP

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0084587-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300475-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0303159-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0303160-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0084587-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0300475-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0303159-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0303160-3-prime-utr Drosophila melanogaster

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Other

5 Pathways

2 Cross References

Identifier
Source . Name
Subject . Primary Identifier
326255 NCBI Entrez Gene identifiers FBgn0053100
77505 BioGRID FBgn0053100

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier
Submission . Title
Cell Line . Name
Developmental Stage . Name 		Score
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 623.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 789.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 631.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 393.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 496.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 776.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 608.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 560.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 458.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 682.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 562.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 559.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 680.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 512.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 672.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 721.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 878.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 580.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 445.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 696.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 644.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 927.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 910.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1783.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 801.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2686.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 604.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 880.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 729.0
FBgn0053100 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 636.0

7 Introns

DB identifier
Organism . Name
intron_FBgn0053100:8_FBgn0053100:7 Drosophila melanogaster
intron_FBgn0053100:7_FBgn0053100:3 Drosophila melanogaster
intron_FBgn0053100:3_FBgn0053100:1 Drosophila melanogaster
intron_FBgn0053100:7_FBgn0053100:6 Drosophila melanogaster
intron_FBgn0053100:6_FBgn0053100:5 Drosophila melanogaster
intron_FBgn0053100:7_FBgn0053100:4 Drosophila melanogaster
intron_FBgn0053100:3_FBgn0053100:2 Drosophila melanogaster

13 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage 4EHP none 1.11510684   19067489
Lipid storage 4EHP none 1.861447724   19067489
Lipid storage 4EHP none -0.562347394   19067489
Lipid storage 4EHP none -1.830506862   19067489
Cell size and cell-cycle regulation (1) 4EHP none sp   16496002
Muscle morphogenesis and function (1) 4EHP none np   20220848
Muscle morphogenesis and function (1) 4EHP Lethal np   20220848
Heart development and function (1) 4EHP none 1   20371351
Heart development and function (1) 4EHP none 1   20371351
Notch pathway regulation (4) 4EHP Notum malformation death 7   19363474
Notch pathway regulation (4) 4EHP Bristle morphology defects, notum malformation death sp   19363474
Self-renewal and differentiation in neural stem cells 4EHP Ganglion mother cell shorter lineages, neuroblast underproliferation, lethal sp   21549331
Hippo pathway regulation 4EHP none -0.57   23263283

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