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Gene : Nhe2 D. melanogaster

DB identifier  ? FBgn0040297 Secondary Identifier  ? CG9256
Name  ? Na[+]/H[+] hydrogen exchanger 2 Source  FlyBase
  • synonyms:
  • FBgn0040297,
  • FBgn0032918,
  • FBgn0032917,
  • CG9255,
  • FBan0009256,
  • DmNHE2,
  • CG9256,
  • NHE2

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26 Alleles

DB identifier Symbol Allele Class Organism
FBal0283451 Nhe2[MI07035]   Drosophila melanogaster
FBal0264097 Nhe2[MI03660]   Drosophila melanogaster
FBal0182497 Nhe2[DG03109]   Drosophila melanogaster
FBal0284996 Nhe2[Scer\UAS.T:Avic\GFP-YFP]   Drosophila melanogaster
FBal0182493 Nhe2[e02060]   Drosophila melanogaster
FBal0182495 Nhe2[d05535]   Drosophila melanogaster
FBal0182491 Nhe2[e04003]   Drosophila melanogaster
FBal0182492 Nhe2[e02882]   Drosophila melanogaster
FBal0182494 Nhe2[e00789]   Drosophila melanogaster
FBal0182496 Nhe2[c04760]   Drosophila melanogaster
FBal0160133 Nhe2[EY11323]   Drosophila melanogaster
FBal0137578 Nhe2[KG03334]   Drosophila melanogaster
FBal0241142 Nhe2[1]   Drosophila melanogaster
FBal0241144 Nhe2[short.Scer\UAS]   Drosophila melanogaster
FBal0241143 Nhe2[long.Scer\UAS]   Drosophila melanogaster
FBal0241145 Nhe2[dsRNA.Scer\UAS.WIZ]   Drosophila melanogaster
FBal0280717 Nhe2[MI07256]   Drosophila melanogaster
FBal0266682 Nhe2[MI04913]   Drosophila melanogaster
FBal0214624 Nhe2[GD3477]   Drosophila melanogaster
FBal0264619 Nhe2[MI03496]   Drosophila melanogaster
FBal0228204 Nhe2[KG02296]   Drosophila melanogaster
FBal0228205 Nhe2[f01515]   Drosophila melanogaster
FBal0228206 Nhe2[KG00359]   Drosophila melanogaster
FBal0228207 Nhe2[KG06975]   Drosophila melanogaster
FBal0231837 Nhe2[KK102518]   Drosophila melanogaster
FBal0276343 Nhe2[NIG.9256R]   Drosophila melanogaster

66 Clones

Secondary Identifier DB identifier
AT12693 FBcl0015823
AT04839 FBcl0016599
AT11019 FBcl0016613
AT08048 FBcl0016659
bs59b05 FBcl0049579
EK244759 FBcl0076236
EK237348 FBcl0076318
EK122025 FBcl0076426
EK001027 FBcl0076510
EK213355 FBcl0076550
EK290637 FBcl0076572
EK217330 FBcl0076598
EK234346 FBcl0076622
EK242613 FBcl0076686
EK254427 FBcl0076708
EK115435 FBcl0076730
EK114514 FBcl0076754
EK252701 FBcl0076776
EK165213 FBcl0076798
EK304334 FBcl0076818
EK249117 FBcl0076840
EK192543 FBcl0076904
EK170135 FBcl0076924
EK262256 FBcl0076948
EP04342 FBcl0078331
EP12241 FBcl0078333
EP13806 FBcl0078355
EP03655 FBcl0078357
EP17854 FBcl0078361
EP07401 FBcl0078363

35 Exons

DB identifier Symbol
FBgn0040297:1 Nhe2:1
FBgn0040297:4 Nhe2:4
FBgn0040297:5 Nhe2:5
FBgn0040297:6 Nhe2:6
FBgn0040297:7 Nhe2:7
FBgn0040297:8 Nhe2:8
FBgn0040297:9 Nhe2:9
FBgn0040297:10 Nhe2:10
FBgn0040297:11 Nhe2:11
FBgn0040297:12 Nhe2:12
FBgn0040297:16 Nhe2:16
FBgn0040297:17 Nhe2:17
FBgn0040297:19 Nhe2:19
FBgn0040297:20 Nhe2:20
FBgn0040297:22 Nhe2:22
FBgn0040297:24 Nhe2:24
FBgn0040297:27 Nhe2:27
FBgn0040297:29 Nhe2:29
FBgn0040297:34 Nhe2:34
FBgn0040297:21 Nhe2:21
FBgn0040297:28 Nhe2:28
FBgn0040297:30 Nhe2:30
FBgn0040297:33 Nhe2:33
FBgn0040297:3 Nhe2:3
FBgn0040297:18 Nhe2:18
FBgn0040297:23 Nhe2:23
FBgn0040297:25 Nhe2:25
FBgn0040297:26 Nhe2:26
FBgn0040297:15 Nhe2:15
FBgn0040297:2 Nhe2:2

12 Transcripts

DB identifier Gene
FBtr0334173 Nhe2
FBtr0299910 Nhe2
FBtr0081466 Nhe2
FBtr0334172 Nhe2
FBtr0306015 Nhe2
FBtr0306016 Nhe2
FBtr0299908 Nhe2
FBtr0299912 Nhe2
FBtr0299909 Nhe2
FBtr0081467 Nhe2
FBtr0334171 Nhe2
FBtr0299911 Nhe2

24 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0081466-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0081467-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0306015-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0306016-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0299908-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0299909-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0299910-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0299911-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0299912-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0334171-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0334172-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0334173-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0081466-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0081467-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0306015-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0306016-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0299908-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0299909-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0299910-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0299911-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0299912-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0334171-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0334172-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0334173-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
35376 NCBI Entrez Gene identifiers FBgn0040297
61332 BioGRID FBgn0040297

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 654.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 568.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1660.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 832.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 984.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 580.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2813.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 870.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 573.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1113.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 718.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1257.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 766.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1912.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 854.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 447.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 803.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1647.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 561.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 825.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 615.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 774.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 705.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 826.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1252.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 273.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1273.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1958.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1165.0
FBgn0040297 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 794.0

43 Introns

DB identifier
Organism . Name
intron_FBgn0040297:2_FBgn0040297:4 Drosophila melanogaster
intron_FBgn0040297:4_FBgn0040297:5 Drosophila melanogaster
intron_FBgn0040297:5_FBgn0040297:6 Drosophila melanogaster
intron_FBgn0040297:6_FBgn0040297:7 Drosophila melanogaster
intron_FBgn0040297:7_FBgn0040297:8 Drosophila melanogaster
intron_FBgn0040297:8_FBgn0040297:9 Drosophila melanogaster
intron_FBgn0040297:9_FBgn0040297:10 Drosophila melanogaster
intron_FBgn0040297:10_FBgn0040297:11 Drosophila melanogaster
intron_FBgn0040297:11_FBgn0040297:12 Drosophila melanogaster
intron_FBgn0040297:12_FBgn0040297:15 Drosophila melanogaster
intron_FBgn0040297:15_FBgn0040297:17 Drosophila melanogaster
intron_FBgn0040297:17_FBgn0040297:19 Drosophila melanogaster
intron_FBgn0040297:19_FBgn0040297:20 Drosophila melanogaster
intron_FBgn0040297:20_FBgn0040297:21 Drosophila melanogaster
intron_FBgn0040297:21_FBgn0040297:25 Drosophila melanogaster
intron_FBgn0040297:25_FBgn0040297:26 Drosophila melanogaster
intron_FBgn0040297:26_FBgn0040297:27 Drosophila melanogaster
intron_FBgn0040297:27_FBgn0040297:28 Drosophila melanogaster
intron_FBgn0040297:28_FBgn0040297:34 Drosophila melanogaster
intron_FBgn0040297:20_FBgn0040297:22 Drosophila melanogaster
intron_FBgn0040297:22_FBgn0040297:25 Drosophila melanogaster
intron_FBgn0040297:28_FBgn0040297:35 Drosophila melanogaster
intron_FBgn0040297:28_FBgn0040297:31 Drosophila melanogaster
intron_FBgn0040297:28_FBgn0040297:32 Drosophila melanogaster
intron_FBgn0040297:32_FBgn0040297:35 Drosophila melanogaster
intron_FBgn0040297:25_FBgn0040297:27 Drosophila melanogaster
intron_FBgn0040297:11_FBgn0040297:13 Drosophila melanogaster
intron_FBgn0040297:12_FBgn0040297:14 Drosophila melanogaster
intron_FBgn0040297:1_FBgn0040297:4 Drosophila melanogaster
intron_FBgn0040297:12_FBgn0040297:16 Drosophila melanogaster

12 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Nhe2 none 1.995605813   19067489
Lipid storage Nhe2 none 0.66627133   19067489
Lipid storage Nhe2 none 0.135601791   19067489
Lipid storage Nhe2 none -0.511923438   19067489
Cell size and cell-cycle regulation (1) Nhe2 none sp   16496002
Muscle morphogenesis and function (1) Nhe2 none np   20220848
RTK-Ras-ERK pathway regulation (1) Nhe2 Increased ERK phosphorylation after EGF stimulation 1.79 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Nhe2 none -0.3 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Nhe2 none -0.2 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Nhe2 none 0.76 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation Nhe2 none 2.42   23263283
Glycosylation regulation (1) Nhe2 none sp   21203496

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