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Gene : eIF3-S10 D. melanogaster

DB identifier  ? FBgn0037249 Secondary Identifier  ? CG9805
Name  ? eIF3-S10 Source  FlyBase
  • synonyms:
  • FBgn0062137,
  • MMAP140,
  • EIF3-S10,
  • anon-WO0118547.261,
  • FBan0009805,
  • FBgn0037249,
  • CG9805

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12 Alleles

DB identifier Symbol Allele Class Organism
FBal0211975 eIF3-S10[CB05493]   Drosophila melanogaster
FBal0245901 eIF3-S10[JF01699]   Drosophila melanogaster
FBal0155364 eIF3-S10[EY04238]   Drosophila melanogaster
FBal0180044 eIF3-S10[e03075]   Drosophila melanogaster
FBal0257935 eIF3-S10[HMS01342]   Drosophila melanogaster
FBal0262422 eIF3-S10[CPTI000076]   Drosophila melanogaster
FBal0286757 eIF3-S10[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286758 eIF3-S10[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0242304 eIF3-S10[JF02719]   Drosophila melanogaster
FBal0209473 eIF3-S10[GD12569]   Drosophila melanogaster
FBal0221997 eIF3-S10[UM-8038-3]   Drosophila melanogaster
FBal0276575 eIF3-S10[NIG.9805R]   Drosophila melanogaster

339 Clones

Secondary Identifier DB identifier
AT17838 FBcl0021007
AT30875 FBcl0021017
AT12348 FBcl0021021
EK227948 FBcl0004904
EK238124 FBcl0004948
EK295324 FBcl0005034
EK042354 FBcl0005154
EK209012 FBcl0005198
EK259554 FBcl0005404
EK068940 FBcl0009412
EK085732 FBcl0014956
EK295204 FBcl0015110
EK068348 FBcl0015452
EK241754 FBcl0015610
EK100212 FBcl0015692
EK054544 FBcl0015776
EK123842 FBcl0015862
EK177421 FBcl0016594
CK01119 FBcl0059607
EN06616 FBcl0094947
EN16830 FBcl0094961
EN05542 FBcl0094965
EN06641 FBcl0094967
GH21513 FBcl0106995
GH21793 FBcl0106997
GH21046 FBcl0107009
GH08334 FBcl0107029
GH07137 FBcl0108693
GH11953 FBcl0108891
GM01640 FBcl0140865

4 Exons

DB identifier Symbol
FBgn0037249:4 eIF3-S10:4
FBgn0037249:3 eIF3-S10:3
FBgn0037249:2 eIF3-S10:2
FBgn0037249:1 eIF3-S10:1

1 Transcripts

DB identifier Gene
FBtr0078944 eIF3-S10

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0078944-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0078944-3-prime-utr Drosophila melanogaster

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43 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
40563 NCBI Entrez Gene identifiers FBgn0037249
65782 BioGRID FBgn0037249

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 3727.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 3838.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 2822.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 3121.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 3357.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 2366.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 3804.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 3800.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1509.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 3027.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 3262.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1842.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 2734.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 3135.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2987.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 3276.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 3087.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 2543.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 3216.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 2799.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 3875.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 3546.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2409.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2771.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1946.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 5107.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 5275.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 4656.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 3633.0
FBgn0037249 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 3620.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0037249:4_FBgn0037249:3 Drosophila melanogaster
intron_FBgn0037249:3_FBgn0037249:2 Drosophila melanogaster
intron_FBgn0037249:2_FBgn0037249:1 Drosophila melanogaster

29 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage eIF3-S10 Increased lipid droplet area 6.569141124   19067489
Lipid storage eIF3-S10 Increased lipid droplet area 5.597274363   19067489
ERK signaling eIF3-S10 ERK activation reduced strong   17086199
Drosophila C virus infection eIF3-S10 Drosophila C virus replication down np   17040126
Cytokinesis regulation eIF3-S10 Binucleate cells with decreased viability weak   15547975
Constitutive protein secretion and Golgi organization (1) eIF3-S10 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) eIF3-S10 Increased G1 DNA content, decreased G2 DNA content, decreased G1 cell size, decreased G2 cell size sp   16496002
Cell size and cell-cycle regulation (2) eIF3-S10 none 1.088   16496002
Cell size and cell-cycle regulation (3) eIF3-S10 none 428   16496002
C. trachomatis infection eIF3-S10 C. trachomatis infection up np   18369471
Mitochondrial biogenesis and function eIF3-S10 Increased mitochondrial citrate synthase activity, decreased viability 1.355   18042644
Microtubule assembly and organization eIF3-S10 none np   18463163
Mutant human huntingtin aggregation eIF3-S10 Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) eIF3-S10 Lethal np   20220848
Heat nociception (1) eIF3-S10 Developmentally lethal 0   21074052
Heart development and function (1) eIF3-S10 Embryonic lethal or no offspring 0   20371351
Serratia marcescens infection (1) eIF3-S10 Decreased viability after Serratia marcescens infection -2.8   19520911
Notch pathway regulation (4) eIF3-S10 Completely lethal (before pupal) sp   19363474
Blood cell homeostasis regulation (1) eIF3-S10 Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (2) eIF3-S10 Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (3) eIF3-S10 none 4.3   20540764
Blood cell homeostasis regulation (4) eIF3-S10 none 1.7   20540764
Blood cell homeostasis regulation (5) eIF3-S10 none 0   20540764
RTK-Ras-ERK pathway regulation (1) eIF3-S10 Decreased ERK phosphorylation after EGF stimulation -2.42 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) eIF3-S10 Decreased ERK phosphorylation after EGF stimulation -4.1 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) eIF3-S10 none 0.59 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) eIF3-S10 Increased ERK phosphorylation after sSpitz and EGF stimulation 1.61 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation eIF3-S10 none -1.6   23263283
Glycosylation regulation (1) eIF3-S10 Lethal np   21203496

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