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Gene : MED19 D. melanogaster

DB identifier  ? FBgn0036761 Secondary Identifier  ? CG5546
Name  ? Mediator complex subunit 19 Source  FlyBase
  • synonyms:
  • FBan0005546,
  • FBgn0036761,
  • CG5546

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7 Alleles

DB identifier Symbol Allele Class Organism
FBal0257274 MED19[HMS00588]   Drosophila melanogaster
FBal0161267 MED19[f07123]   Drosophila melanogaster
FBal0197705 MED19[dsRNA.cMa]   Drosophila melanogaster
FBal0232032 MED19[KK102825]   Drosophila melanogaster
FBal0242298 MED19[JF02713]   Drosophila melanogaster
FBal0207552 MED19[GD11688]   Drosophila melanogaster
FBal0274724 MED19[NIG.5546R]   Drosophila melanogaster

81 Clones

Secondary Identifier DB identifier
EP10725 FBcl0079657
EN10018 FBcl0094621
EK184351 FBcl0094696
LD41305 FBcl0163392
LD41395 FBcl0163447
LD43231 FBcl0163448
LD38373 FBcl0163538
LD44024 FBcl0163539
LP12065 FBcl0179497
RE42786 FBcl0193067
RE41623 FBcl0193086
RE64793 FBcl0193159
RE73251 FBcl0193173
RE08336 FBcl0193339
RH54976 FBcl0240999
RH44010 FBcl0241023
RH49683 FBcl0241219
RH68387 FBcl0241221
SD27347 FBcl0281494
SD16817 FBcl0281497
SD27820 FBcl0281499
SD16370 FBcl0281503
EC053377 FBcl0302653
FGH120H01 FBcl0388092
FGM001D12 FBcl0388771
CK01.1B.F7 FBcl0459829
533999 FBcl0459833
RP003443553 FBcl0686688
RP003340799 FBcl0686685
RP003477082 FBcl0686686

3 Exons

DB identifier Symbol
FBgn0036761:3 MED19:3
FBgn0036761:2 MED19:2
FBgn0036761:1 MED19:1

1 Transcripts

DB identifier Gene
FBtr0075160 MED19

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0075160-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075160-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
39987 NCBI Entrez Gene identifiers FBgn0036761
65272 BioGRID FBgn0036761

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 771.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 878.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 436.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 595.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 544.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 427.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 698.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 658.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 461.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 640.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 613.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 413.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 460.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 729.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 771.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 433.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 689.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 456.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 508.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 458.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 804.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 755.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 519.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 759.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 536.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2511.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 654.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1060.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 835.0
FBgn0036761 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1055.0

2 Introns

DB identifier
Organism . Name
intron_FBgn0036761:3_FBgn0036761:2 Drosophila melanogaster
intron_FBgn0036761:2_FBgn0036761:1 Drosophila melanogaster

19 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage MED19 Decreased lipid droplet area -3.138930926   19067489
Lipid storage MED19 Decreased lipid droplet area -1.395608895   19067489
Lipid storage MED19 Decreased lipid droplet area -3.421833481   19067489
ERK signaling MED19 ERK activation increased strong   17086199
Constitutive protein secretion and Golgi organization (1) MED19 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) MED19 none sp   16496002
Combinatorial effect with methyl methanesulphonate (2) MED19 Synthetic lethal with methyl methanesulphonate sp   19543366
Muscle morphogenesis and function (1) MED19 none np   20220848
Heart development and function (1) MED19 none 1   20371351
Notch pathway regulation (4) MED19 Completely lethal (pupal) sp   19363474
PGN-induced dJNK phosphorylation MED19 Increased P-JNK protein expression with PGN 4.06 15 min PGN induction 19893628
PGN-induced dJNK phosphorylation MED19 Increased P-JNK protein expression with PGN 2.4 60 min PGN induction 19893628
RTK-Ras-ERK pathway regulation (1) MED19 none 0.46 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) MED19 none 0.64 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) MED19 Increased ERK phosphorylation after sSpitz and EGF stimulation 2.16 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) MED19 Increased ERK phosphorylation after sSpitz and EGF stimulation 3.91 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation MED19 none -1.21   23263283
Srp/Lz-induced transcriptional activation MED19 Decreased Srp/Lz-induced transcription -14.09   20368357
Glycosylation regulation (1) MED19 none sp   21203496

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