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Gene : ACC D. melanogaster

DB identifier  ? FBgn0033246 Secondary Identifier  ? CG11198
Name  ? Acetyl-CoA carboxylase Source  FlyBase
  • synonyms:
  • acetyl coenzyme A carboxylase,
  • FBan0011198,
  • Acetyl-CoA carboxylase,
  • FBgn0033246,
  • ACC,
  • dACC,
  • FBgn0043811,
  • CG8723,
  • CG11198,
  • FBgn0033245,
  • DmACC,
  • acetyl-coenzyme A carboxylase,
  • Acetyl CoA carboxylase,
  • A1Z784_DROME

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7 Alleles

DB identifier Symbol Allele Class Organism
FBal0283268 ACC[Scer\UAS.cPa]   Drosophila melanogaster
FBal0268922 ACC[TR00325A.1]   Drosophila melanogaster
FBal0263243 ACC[HMS01230]   Drosophila melanogaster
FBal0265260 ACC[MI03343]   Drosophila melanogaster
FBal0199320 ACC[GD3482]   Drosophila melanogaster
FBal0231618 ACC[KK102082]   Drosophila melanogaster
FBal0217048 ACC[B131]   Drosophila melanogaster

52 Clones

Secondary Identifier DB identifier
AT18691 FBcl0030367
AT26094 FBcl0030379
AT26769 FBcl0030381
EP08843 FBcl0084849
EP06430 FBcl0084865
GH27434 FBcl0130273
GH06401 FBcl0130307
GH03417 FBcl0130323
GH09643 FBcl0130329
GH02896 FBcl0130363
GH27592 FBcl0130579
GH27615 FBcl0130799
GH23405 FBcl0130817
GH12002 FBcl0130821
EK158835 FBcl0135228
EK290638 FBcl0135266
EK305842 FBcl0135278
EK198146 FBcl0135280
EK254415 FBcl0135284
EK166403 FBcl0135286
EK131739 FBcl0135344
GM12430 FBcl0147042
GM13122 FBcl0147043
HL06632 FBcl0150359
HL03945 FBcl0150362
HL02902 FBcl0150390
HL07422 FBcl0150393
HL01362 FBcl0150397
SD10287 FBcl0287080
SD06750 FBcl0287084

18 Exons

DB identifier Symbol
FBgn0033246:16 ACC:16
FBgn0033246:14 ACC:14
FBgn0033246:13 ACC:13
FBgn0033246:12 ACC:12
FBgn0033246:10 ACC:10
FBgn0033246:9 ACC:9
FBgn0033246:8 ACC:8
FBgn0033246:7 ACC:7
FBgn0033246:6 ACC:6
FBgn0033246:5 ACC:5
FBgn0033246:4 ACC:4
FBgn0033246:3 ACC:3
FBgn0033246:2 ACC:2
FBgn0033246:1 ACC:1
FBgn0033246:15 ACC:15
FBgn0033246:11 ACC:11
FBgn0033246:17 ACC:17
FBgn0033246:18 ACC:18

6 Transcripts

DB identifier Gene
FBtr0088872 ACC
FBtr0088871 ACC
FBtr0113053 ACC
FBtr0339124 ACC
FBtr0339125 ACC
FBtr0339123 ACC

12 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0088871-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0088872-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0113053-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0339123-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0339124-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0339125-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088871-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088872-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0113053-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0339123-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0339124-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0339125-3-prime-utr Drosophila melanogaster

Interactions

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Other

67 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
35761 NCBI Entrez Gene identifiers FBgn0033246
61622 BioGRID FBgn0033246

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 2197.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2018.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 2462.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 2806.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1670.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1054.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 3155.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 3252.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1943.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1922.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1606.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1256.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 2031.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2023.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2755.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1582.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1998.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1922.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1416.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1786.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 3027.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2636.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1770.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1828.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1686.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2418.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 339.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 271.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 269.0
FBgn0033246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 530.0

18 Introns

DB identifier
Organism . Name
intron_FBgn0033246:11_FBgn0033246:10 Drosophila melanogaster
intron_FBgn0033246:10_FBgn0033246:9 Drosophila melanogaster
intron_FBgn0033246:9_FBgn0033246:8 Drosophila melanogaster
intron_FBgn0033246:8_FBgn0033246:7 Drosophila melanogaster
intron_FBgn0033246:7_FBgn0033246:6 Drosophila melanogaster
intron_FBgn0033246:6_FBgn0033246:5 Drosophila melanogaster
intron_FBgn0033246:5_FBgn0033246:4 Drosophila melanogaster
intron_FBgn0033246:4_FBgn0033246:3 Drosophila melanogaster
intron_FBgn0033246:3_FBgn0033246:2 Drosophila melanogaster
intron_FBgn0033246:2_FBgn0033246:1 Drosophila melanogaster
intron_FBgn0033246:18_FBgn0033246:13 Drosophila melanogaster
intron_FBgn0033246:13_FBgn0033246:12 Drosophila melanogaster
intron_FBgn0033246:12_FBgn0033246:10 Drosophila melanogaster
intron_FBgn0033246:16_FBgn0033246:14 Drosophila melanogaster
intron_FBgn0033246:14_FBgn0033246:13 Drosophila melanogaster
intron_FBgn0033246:16_FBgn0033246:13 Drosophila melanogaster
intron_FBgn0033246:15_FBgn0033246:13 Drosophila melanogaster
intron_FBgn0033246:17_FBgn0033246:13 Drosophila melanogaster

31 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage ACC none 1.485699569   19067489
Lipid storage ACC none 1.523515367   19067489
Lipid storage ACC none -2.321584545   19067489
Lipid storage ACC none -1.186330774   19067489
ERK signaling ACC ERK activation reduced strong   17086199
Drosophila C virus infection ACC Drosophila C virus replication down np   17040126
Intracellular Listeria monocytogenes infection ACC Decreased GFP protein expression strong   16020693
Hedgehog signaling ACC Decreased Hedgehog reporter activity -2.08   16311596
Mycobacterial infection (1) - M. fortuitum infection ACC Decreased M. fortuitum intracellular infection 7.4 measurement after 3 days 16020694
Mycobacterial infection (2) - E. coli phagocytosis ACC Decreased E. coli phagocytosis np   16020694
Constitutive protein secretion and Golgi organization (1) ACC Decreased horseradish peroxidase protein expression sp   16452979
Constitutive protein secretion and Golgi organization (1) ACC Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) ACC none sp   16496002
Cell size and cell-cycle regulation (1) ACC none sp   16496002
Muscle morphogenesis and function (1) ACC Locomotion defect np   20220848
Heat nociception (1) ACC none -1.17   21074052
Heart development and function (1) ACC Pupal lethal 0.33   20371351
Serratia marcescens infection (1) ACC none 0.210526315789473   19520911
Notch pathway regulation (4) ACC Completely lethal (pupal) sp   19363474
Hh pathway regulation ACC none -0.116418640789777   17903264
Hh pathway regulation ACC none -0.0683694373700249   17903264
Self-renewal and differentiation in neural stem cells ACC GFP aggregates number, GFP aggregates size, lethal sp   21549331
Notch pathway regulation (3) ACC Only lethal with Notch np   20493818
Notch pathway regulation (4) ACC Lethal strong en-GAL4 20493818
Adiposity regulation (1) ACC none -0.334   20074523
S2 cell spreading ACC Increased actin protein expression at cell perimeter on Con A surface sp   21041442
RTK-Ras-ERK pathway regulation (1) ACC Decreased ERK phosphorylation after EGF stimulation -1.81 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) ACC Increased ERK phosphorylation after EGF stimulation 2.02 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) ACC none -0.58 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) ACC none 0.42 10 minutes sSpitz stimulation 22028469

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