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Gene : VhaPPA1-1 D. melanogaster

DB identifier  ? FBgn0028662 Secondary Identifier  ? CG7007
Name  ? Vacuolar H[+] ATPase PPA1 subunit 1 Source  FlyBase
  • synonyms:
  • V-ATPase proton pump,
  • FBgn0038278,
  • CG7007,
  • VhaPPA1,
  • FBan0007007,
  • FBgn0028662,
  • VhaPPA1-1,
  • Vacuolar H[+] ATPase subunit PPA1-1

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6 Alleles

DB identifier Symbol Allele Class Organism
FBal0211958 VhaPPA1-1[CB02209]   Drosophila melanogaster
FBal0181060 VhaPPA1-1[e03223]   Drosophila melanogaster
FBal0155713 VhaPPA1-1[EP3504]   Drosophila melanogaster
FBal0208976 VhaPPA1-1[GD2991]   Drosophila melanogaster
FBal0208977 VhaPPA1-1[GD16478]   Drosophila melanogaster
FBal0275379 VhaPPA1-1[NIG.7007R]   Drosophila melanogaster

194 Clones

Secondary Identifier DB identifier
AT23264 FBcl0042039
EK197956 FBcl0053356
EK211409 FBcl0053612
EK293313 FBcl0053638
EK152345 FBcl0053642
EK042820 FBcl0053662
EK154235 FBcl0054158
EK094801 FBcl0054354
EK120711 FBcl0054384
bs32f08 FBcl0057599
bs08b03 FBcl0057605
EP12362 FBcl0088951
EN05129 FBcl0101515
GH24625 FBcl0128075
GH27747 FBcl0128077
GH24369 FBcl0128187
GH27165 FBcl0129615
GH12871 FBcl0129715
GH03514 FBcl0129739
GH03023 FBcl0129753
GM05062 FBcl0143531
GM15686 FBcl0148262
LD17944 FBcl0160613
LD31919 FBcl0174966
LD45146 FBcl0176071
LP09105 FBcl0188435
LP21901 FBcl0188550
LP03388 FBcl0188811
LP22247 FBcl0189145
LP18263 FBcl0189171

4 Exons

DB identifier Symbol
FBgn0028662:4 VhaPPA1-1:4
FBgn0028662:3 VhaPPA1-1:3
FBgn0028662:1 VhaPPA1-1:1
FBgn0028662:2 VhaPPA1-1:2

2 Transcripts

DB identifier Gene
FBtr0308030 VhaPPA1-1
FBtr0083005 VhaPPA1-1

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0083005-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0308030-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0083005-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0308030-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
45247 NCBI Entrez Gene identifiers FBgn0028662
69537 BioGRID FBgn0028662

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1748.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2280.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1251.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1796.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1780.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 2178.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2193.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 3014.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 2342.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1969.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2402.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1699.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1919.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1205.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1308.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 2116.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1435.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1626.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 2512.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1704.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1786.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 3262.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1580.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2483.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1265.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3089.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1865.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1410.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1407.0
FBgn0028662 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1299.0

4 Introns

DB identifier
Organism . Name
intron_FBgn0028662:4_FBgn0028662:3 Drosophila melanogaster
intron_FBgn0028662:3_FBgn0028662:1 Drosophila melanogaster
intron_FBgn0028662:4_FBgn0028662:2 Drosophila melanogaster
intron_FBgn0028662:2_FBgn0028662:1 Drosophila melanogaster

36 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage VhaPPA1-1 none -0.17884171   19067489
Lipid storage VhaPPA1-1 none 2.658264056   19067489
Insect dengue virus infection VhaPPA1-1 Inhibition of dengue virus propagation 10.9 (0.0000043)   19396146
Chlamydia caviae infection VhaPPA1-1 Decreased Chlamydia caviae infection np   17967059
Cell size and cell-cycle regulation (1) VhaPPA1-1 none sp   16496002
Mitosis VhaPPA1-1 Spindle pole detachment np   17412918
Combinatorial effect with methyl methanesulphonate (2) VhaPPA1-1 Synthetic lethal with methyl methanesulphonate sp   19543366
Muscle morphogenesis and function (1) VhaPPA1-1 Lethal np   20220848
Muscle morphogenesis and function (1) VhaPPA1-1 Lethal np   20220848
Muscle morphogenesis and function (1) VhaPPA1-1 Lethal np   20220848
Muscle morphogenesis and function (3) VhaPPA1-1 Spotty (discontinuous) Z-line np   20220848
Heat nociception (1) VhaPPA1-1 Increased noxious heat avoidance 5.9   21074052
Heat nociception (1) VhaPPA1-1 none 0.9   21074052
Heat nociception (1) VhaPPA1-1 Increased noxious heat avoidance, lethal 3.83   21074052
Heat nociception (1) VhaPPA1-1 Developmentally lethal -1.17   21074052
Heart development and function (1) VhaPPA1-1 Adult lethal 0.5   20371351
Heart development and function (1) VhaPPA1-1 none 1   20371351
Heart development and function (2) VhaPPA1-1 Decreased viability 3.73   20371351
Serratia marcescens infection (1) VhaPPA1-1 none 0.12037037037037   19520911
Serratia marcescens infection (1) VhaPPA1-1 none -0.911764705882352   19520911
Serratia marcescens infection (1) VhaPPA1-1 none -0.734375   19520911
Notch pathway regulation (4) VhaPPA1-1 Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) VhaPPA1-1 Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) VhaPPA1-1 Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) VhaPPA1-1 Gain of bristles, colour defects, notum malformation death sp   19363474
Notch pathway regulation (1) VhaPPA1-1 Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) VhaPPA1-1 Lethal strong en-GAL4 20493818
Notch pathway regulation (2) VhaPPA1-1 Lethal strong en-GAL4 20493818
Notch pathway regulation (2) VhaPPA1-1 Downregulation of Notch pathway; adult wing margin: notches sp C96-GAL4 20493818
Notch pathway regulation (2) VhaPPA1-1 Up- and downregulation of Notch pathway; adult wing margin: notches; wing pouch: spoon-like sp C96-GAL4 20493818

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