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Gene : Cdk9 D. melanogaster

DB identifier  ? FBgn0019949 Secondary Identifier  ? CG5179
Name  ? Cyclin-dependent kinase 9 Source  FlyBase
  • synonyms:
  • Positive transcription elongation factor b,
  • FBgn0019949,
  • Cyclin-dependent kinase9 2.7,
  • Positive transcription elongation factor b, small subunit,
  • FBan0005179,
  • P-TEFb,
  • PTefb,
  • CDK9,
  • p43 PITALRE,
  • CG5179,
  • P-TEF

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18 Alleles

DB identifier Symbol Allele Class Organism
FBal0160705 Cdk9[f05537]   Drosophila melanogaster
FBal0152678 Cdk9[tGa]   Drosophila melanogaster
FBal0152676 Cdk9[tGc]   Drosophila melanogaster
FBal0152677 Cdk9[tGb]   Drosophila melanogaster
FBal0184353 Cdk9[dsRNA.cNa]   Drosophila melanogaster
FBal0262701 Cdk9[GL00230]   Drosophila melanogaster
FBal0105259 Cdk9[D199N.MtnA.T:Scer\GAL4]   Drosophila melanogaster
FBal0105258 Cdk9[MtnA.T:Scer\GAL4]   Drosophila melanogaster
FBal0105257 Cdk9[MtnA.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0263301 Cdk9[HMS01391]   Drosophila melanogaster
FBal0286995 Cdk9[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286996 Cdk9[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0206546 Cdk9[GD4078]   Drosophila melanogaster
FBal0216734 Cdk9[nos.3'UTR.Scer\UAS.P\T]   Drosophila melanogaster
FBal0279328 Cdk9[HMS02329]   Drosophila melanogaster
FBal0222146 Cdk9[NP0727]   Drosophila melanogaster
FBal0231119 Cdk9[KK101197]   Drosophila melanogaster
FBal0274557 Cdk9[NIG.5179R]   Drosophila melanogaster

71 Clones

Secondary Identifier DB identifier
EK192413 FBcl0038430
EK243209 FBcl0012882
EK051344 FBcl0012892
AT28202 FBcl0028173
EK259739 FBcl0038536
GH20191 FBcl0123069
GH19370 FBcl0123339
GH21935 FBcl0123411
GM15595 FBcl0146748
GM27181 FBcl0146751
GM14191 FBcl0146753
LD05363 FBcl0158315
LD08792 FBcl0158371
LD09645 FBcl0158372
LD41102 FBcl0172718
LD38011 FBcl0172719
LD45702 FBcl0172720
RE12564 FBcl0220510
RE12621 FBcl0220698
RE14431 FBcl0220788
RE20085 FBcl0220789
RH67555 FBcl0260959
RH69734 FBcl0260961
RH01023 FBcl0260963
RH36556 FBcl0260964
SD23923 FBcl0286183
SD12401 FBcl0286194
SD13015 FBcl0286200
EC054509 FBcl0302450
EC056106 FBcl0302449

4 Exons

DB identifier Symbol
FBgn0019949:4 Cdk9:4
FBgn0019949:3 Cdk9:3
FBgn0019949:2 Cdk9:2
FBgn0019949:1 Cdk9:1

1 Transcripts

DB identifier Gene
FBtr0071937 Cdk9

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0071937-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0071937-3-prime-utr Drosophila melanogaster

Interactions

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
37586 NCBI Entrez Gene identifiers FBgn0019949
63201 BioGRID FBgn0019949

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 694.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1067.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 921.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 670.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 919.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 376.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 739.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 796.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 354.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1642.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 748.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 717.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 453.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 630.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 638.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 596.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 887.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 724.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 719.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 626.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 781.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 793.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 854.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 701.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 356.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1788.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1658.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1297.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1154.0
FBgn0019949 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 807.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0019949:4_FBgn0019949:3 Drosophila melanogaster
intron_FBgn0019949:3_FBgn0019949:2 Drosophila melanogaster
intron_FBgn0019949:2_FBgn0019949:1 Drosophila melanogaster

54 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Cdk9 none 1.911459685   19067489
Lipid storage Cdk9 none 2.349036675   19067489
ERK signaling Cdk9 ERK activation increased weak   17086199
Cell morphology Cdk9 Morphology np   14527345
Cell cycle regulation (1) Cdk9 Increased G1 DNA content, decreased mitotic index sp   15616552
Cell cycle regulation (2) Cdk9 Increased G1 DNA content, increased cell size np   15616552
Hedgehog signaling Cdk9 Decreased Hedgehog reporter activity -2.06   16311596
Constitutive protein secretion and Golgi organization (1) Cdk9 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Cdk9 Increased G2 DNA content sp   16496002
Cell size and cell-cycle regulation (1) Cdk9 none sp   16496002
Cell size and cell-cycle regulation (1) Cdk9 none sp   16496002
Cell size and cell-cycle regulation (2) Cdk9 none 1.189   16496002
Cell size and cell-cycle regulation (3) Cdk9 none 456   16496002
Candida albicans phagocytosis (1) Cdk9 none np   16336044
Dendrite pattern formation Cdk9 none np   16547170
DFoxO signaling Cdk9 Decreased dFoxO reporter activity 0.02   18815370
Lipid storage Cdk9 Smaller sized lipid droplets, more dispersed strong   18408709
Muscle morphogenesis and function (1) Cdk9 Lethal np   20220848
Muscle morphogenesis and function (1) Cdk9 Lethal np   20220848
Muscle morphogenesis and function (2) Cdk9 Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Heat nociception (1) Cdk9 none 0.7   21074052
Heat nociception (1) Cdk9 Increased noxious heat avoidance 1.98   21074052
Heart development and function (1) Cdk9 none 1   20371351
Heart development and function (2) Cdk9 none 2.97   20371351
Serratia marcescens infection (1) Cdk9 none 0.833333333333333   19520911
Notch pathway regulation (4) Cdk9 Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) Cdk9 Completely lethal (before pupal) sp   19363474
Notch induced transcription Cdk9 none -0.35115 N(delta)ecn Notch stimulation 20959007
Notch induced transcription Cdk9 Upregulation of Notch pathway after Notch stimulation 2.3843 N(delta)ecn Notch stimulation 20959007
Notch induced transcription Cdk9 none -1.8009 without Notch stimulation 20959007

0 Submissions