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Gene : fz2 D. melanogaster

DB identifier  ? FBgn0016797 Secondary Identifier  ? CG9739
Name  ? frizzled 2 Source  FlyBase
  • synonyms:
  • DFrizzled2,
  • Dfrz2,
  • Dfz[[2]],
  • FZ2,
  • CG9739,
  • Drosophila Frizzled 2,
  • Dfrizzled[[2]],
  • FBan0009739,
  • Frizzled2,
  • Frizzled 2,
  • D-frizzled2,
  • Frizzled-2,
  • D-Fz2,
  • Dm Fz2,
  • frz2,
  • DFZ2,
  • DFz-2,
  • dfz2r,
  • fz-2,
  • FBgn0016797,
  • dfz(2)

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129 Alleles

DB identifier Symbol Allele Class Organism
FBal0281036 fz2[MI07226]   Drosophila melanogaster
FBal0283761 fz2[C118Y.arm.T:Hsap\MYC]   Drosophila melanogaster
FBal0283762 fz2[R345A.arm.T:Hsap\MYC]   Drosophila melanogaster
FBal0283763 fz2[P349L.arm.T:Hsap\MYC]   Drosophila melanogaster
FBal0283764 fz2[ITAA.arm.T:Hsap\MYC]   Drosophila melanogaster
FBal0283765 fz2[L528A.arm.T:Hsap\MYC]   Drosophila melanogaster
FBal0283766 fz2[K608A.arm.T:Hsap\MYC]   Drosophila melanogaster
FBal0283767 fz2[T609A.arm.T:Hsap\MYC]   Drosophila melanogaster
FBal0283768 fz2[W613A.arm.T:Hsap\MYC]   Drosophila melanogaster
FBal0211986 fz2[CB02997]   Drosophila melanogaster
FBal0256791 fz2[MI01509]   Drosophila melanogaster
FBal0245551 fz2[JF01259]   Drosophila melanogaster
FBal0260468 fz2[MI02902]   Drosophila melanogaster
FBal0245652 fz2[JF01378]   Drosophila melanogaster
FBal0179722 fz2[f07590]   Drosophila melanogaster
FBal0179723 fz2[f01018]   Drosophila melanogaster
FBal0212499 fz2[MB01455]   Drosophila melanogaster
FBal0100365 fz2[469]   Drosophila melanogaster
FBal0179733 fz2[C2.Scer\UAS.T:SS-wg,T:Ivir\HA1]   Drosophila melanogaster
FBal0179730 fz2[C3.Scer\UAS.T:SS-wg,T:Ivir\HA1]   Drosophila melanogaster
FBal0179724 fz2[Scer\UAS.T:SS-wg,T:Ivir\HA1]   Drosophila melanogaster
FBal0179737 fz2[DeltaCRD.alphaTub84B.T:SS-wg,T:Ivir\HA1]   Drosophila melanogaster
FBal0102708 fz2[C1] loss of function allele Drosophila melanogaster
FBal0159196 fz2[dsRNA.cFa]   Drosophila melanogaster
FBal0051541 fz2[MtnA.PB]   Drosophila melanogaster
FBal0102710 fz2[alphaTub84B.PC] wild-type allele Drosophila melanogaster
FBal0120490 fz2[a.916-2204]   Drosophila melanogaster
FBal0130315 fz2[2-2-2.hs.2sev]   Drosophila melanogaster
FBal0130318 fz2[2-2-2.alphaTub84B]   Drosophila melanogaster
FBal0179726 fz2[GSG18.alphaTub84B]   Drosophila melanogaster

466 Clones

Secondary Identifier DB identifier
UUGC0003 FBcl0001043
EK043736 FBcl0031192
EC28507 FBcl0066153
EC21207 FBcl0066155
EC27976 FBcl0066981
EP01612 FBcl0079973
EP18903 FBcl0080289
EK154117 FBcl0137524
EK138360 FBcl0137746
EK161505 FBcl0137784
EK154046 FBcl0137786
EK197960 FBcl0137788
EK187840 FBcl0137796
EK086504 FBcl0137800
EK118754 FBcl0137806
EK201314 FBcl0137808
EK104432 FBcl0137810
EK201264 FBcl0137814
EK021253 FBcl0137820
EK156923 FBcl0137822
EK183738 FBcl0137826
EK286455 FBcl0137828
EK137122 FBcl0137830
EK227558 FBcl0137832
EK047818 FBcl0137836
EK214703 FBcl0137848
EK045305 FBcl0137850
EK059546 FBcl0137852
EK201012 FBcl0137856
EK185238 FBcl0137864

14 Exons

DB identifier Symbol
FBgn0016797:4 fz2:4
FBgn0016797:6 fz2:6
FBgn0016797:13 fz2:13
FBgn0016797:2 fz2:2
FBgn0016797:10 fz2:10
FBgn0016797:8 fz2:8
FBgn0016797:5 fz2:5
FBgn0016797:1 fz2:1
FBgn0016797:7 fz2:7
FBgn0016797:3 fz2:3
FBgn0016797:14 fz2:14
FBgn0016797:12 fz2:12
FBgn0016797:11 fz2:11
FBgn0016797:9 fz2:9

7 Transcripts

DB identifier Gene
FBtr0075029 fz2
FBtr0112890 fz2
FBtr0299586 fz2
FBtr0332735 fz2
FBtr0075028 fz2
FBtr0330194 fz2
FBtr0330195 fz2

14 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0075028-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0075029-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0112890-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0299586-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0330194-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0330195-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0332735-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075028-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075029-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0112890-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0299586-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0330194-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0330195-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0332735-3-prime-utr Drosophila melanogaster

Interactions

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
40090 NCBI Entrez Gene identifiers FBgn0016797
65366 BioGRID FBgn0016797

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from UniProt  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 522.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 728.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 404.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 455.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 226.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 404.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 543.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 114.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 367.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 231.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 446.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 2154.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 380.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 275.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 3726.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 352.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 228.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 360.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 451.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 614.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2466.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 286.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 131.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 340.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 481.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 910.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2741.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 4663.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 4372.0
FBgn0016797 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 6182.0

14 Introns

DB identifier
Organism . Name
intron_FBgn0016797:4_FBgn0016797:3 Drosophila melanogaster
intron_FBgn0016797:8_FBgn0016797:5 Drosophila melanogaster
intron_FBgn0016797:5_FBgn0016797:1 Drosophila melanogaster
intron_FBgn0016797:6_FBgn0016797:5 Drosophila melanogaster
intron_FBgn0016797:5_FBgn0016797:2 Drosophila melanogaster
intron_FBgn0016797:7_FBgn0016797:5 Drosophila melanogaster
intron_FBgn0016797:5_FBgn0016797:3 Drosophila melanogaster
intron_FBgn0016797:14_FBgn0016797:12 Drosophila melanogaster
intron_FBgn0016797:12_FBgn0016797:11 Drosophila melanogaster
intron_FBgn0016797:11_FBgn0016797:9 Drosophila melanogaster
intron_FBgn0016797:9_FBgn0016797:5 Drosophila melanogaster
intron_FBgn0016797:13_FBgn0016797:12 Drosophila melanogaster
intron_FBgn0016797:11_FBgn0016797:10 Drosophila melanogaster
intron_FBgn0016797:10_FBgn0016797:9 Drosophila melanogaster

27 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage fz2 none 0.257946239   19067489
Lipid storage fz2 none -1.208794547   19067489
Lipid storage fz2 none 0.683044175   19067489
Lipid storage fz2 none 1.2210345   19067489
Lipid storage fz2 none -0.476517784   19067489
Lipid storage fz2 none -0.953656944   19067489
Lipid storage fz2 none -0.753470047   19067489
Neural outgrowth fz2 Cell cluster defect np   18604272
ERK signaling fz2 ERK activation increased strong   17086199
Cell size and cell-cycle regulation (1) fz2 none sp   16496002
Cell size and cell-cycle regulation (1) fz2 none sp   16496002
Muscle morphogenesis and function (1) fz2 Semi-lethal np   20220848
Muscle morphogenesis and function (1) fz2 Lethal np   20220848
Heat nociception (1) fz2 none 0.46   21074052
Heat nociception (1) fz2 none 1.15   21074052
Heart development and function (1) fz2 none 1   20371351
Serratia marcescens infection (1) fz2 none -0.828125   19520911
Notch pathway regulation (4) fz2 none 0   19363474
Notch pathway regulation (4) fz2 none 0   19363474
Adiposity regulation (1) fz2 none 0.139   20074523
RTK-Ras-ERK pathway regulation (1) fz2 Increased ERK phosphorylation after EGF stimulation 1.56 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) fz2 none 0.3 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) fz2 none -0.22 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) fz2 none 0.13 30 minutes sSpitz stimulation 22028469
Wnt proteins secretion fz2 none -1.8   22094269
Hippo pathway regulation fz2 none -0.96   23263283
Glycosylation regulation (1) fz2 none sp   21203496

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