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Gene : Trip1 D. melanogaster

DB identifier  ? FBgn0015834 Secondary Identifier  ? CG8882
Name  ? Trip1 Source  FlyBase
  • synonyms:
  • CG8882,
  • DmTRIP,
  • FBgn0015834,
  • eIF-3beta,
  • FBan0008882,
  • eIF3-S2

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4 Alleles

DB identifier Symbol Allele Class Organism
FBal0137340 Trip1[KG06360]   Drosophila melanogaster
FBal0263297 Trip1[HMS01387]   Drosophila melanogaster
FBal0208845 Trip1[GD14057]   Drosophila melanogaster
FBal0235100 Trip1[KK107698]   Drosophila melanogaster

295 Clones

Secondary Identifier DB identifier
AT14303 FBcl0019323
AT05458 FBcl0019411
UUGC0847 FBcl0004731
EK129363 FBcl0031452
EK169210 FBcl0031472
EK197959 FBcl0031482
EK248927 FBcl0031518
EK172527 FBcl0031530
EK056012 FBcl0031578
AT19691 FBcl0041497
bs68h12 FBcl0050443
EC01893 FBcl0065661
EN05006 FBcl0094543
EN08005 FBcl0094547
EN13858 FBcl0094567
EN11004 FBcl0094579
EN07107 FBcl0094581
GH04894 FBcl0131757
GH18335 FBcl0131775
GH14342 FBcl0131835
GH26105 FBcl0131837
GH24962 FBcl0131839
GH18476 FBcl0132135
GH11348 FBcl0132191
GM01509 FBcl0140501
GM10314 FBcl0140509
GM04005 FBcl0140515
GM04041 FBcl0140517
GM02261 FBcl0140519
GM10229 FBcl0140523

3 Exons

DB identifier Symbol
FBgn0015834:3 Trip1:3
FBgn0015834:2 Trip1:2
FBgn0015834:1 Trip1:1

1 Transcripts

DB identifier Gene
FBtr0079053 Trip1

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0079053-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0079053-3-prime-utr Drosophila melanogaster

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43 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
33710 NCBI Entrez Gene identifiers FBgn0015834
59895 BioGRID FBgn0015834

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 2290.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2512.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 2512.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 2358.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 2543.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1439.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1392.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 3086.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1590.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1761.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2321.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1935.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 2364.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1971.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2438.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 2089.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2052.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 2051.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 3135.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 2280.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1897.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1866.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1653.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1515.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1528.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2892.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2978.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2624.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2336.0
FBgn0015834 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 2547.0

2 Introns

DB identifier
Organism . Name
intron_FBgn0015834:3_FBgn0015834:2 Drosophila melanogaster
intron_FBgn0015834:2_FBgn0015834:1 Drosophila melanogaster

33 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Trip1 Increased lipid droplet area 4.301905731   19067489
Lipid storage Trip1 Increased lipid droplet area 4.304944549   19067489
ERK signaling Trip1 ERK activation reduced weak   17086199
Drosophila C virus infection Trip1 Drosophila C virus replication down np   17040126
L. monocytogenes infection Trip1 Escape pff LLO- strain *   16157870
Constitutive protein secretion and Golgi organization (1) Trip1 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Trip1 none sp   16496002
Influenza replication Trip1 Decreased Influenza replication -4.33/-4.51   18615016
Mitochondrial biogenesis and function Trip1 Increased mitochondrial citrate synthase activity, decreased viability 1.336   18042644
Microtubule assembly and organization Trip1 none np   18463163
Muscle morphogenesis and function (1) Trip1 Lethal np   20220848
Muscle morphogenesis and function (1) Trip1 Lethal np   20220848
Muscle morphogenesis and function (2) Trip1 Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Muscle morphogenesis and function (3) Trip1 Clumpy Z-line (irregular aggregates) np   20220848
Heat nociception (1) Trip1 none -1.17   21074052
Heart development and function (1) Trip1 Larval lethal 0   20371351
Serratia marcescens infection (1) Trip1 none 0.37037037037037   19520911
Notch pathway regulation (4) Trip1 Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) Trip1 Completely lethal (pupal) sp   19363474
PGN-induced dJNK phosphorylation Trip1 Increased P-JNK protein expression with PGN 2.1 60 min PGN induction 19893628
Notch induced transcription Trip1 Downregulation of Notch pathway after Notch stimulation -2.0937 N(delta)ecn Notch stimulation 20959007
Notch induced transcription Trip1 none 0.65847 N(delta)ecn Notch stimulation 20959007
Notch induced transcription Trip1 none -1.4767 without Notch stimulation 20959007
Notch pathway regulation (1) Trip1 Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) Trip1 none np en-GAL4 20493818
Notch pathway regulation (3) Trip1 Only lethal with Notch np   20493818
RTK-Ras-ERK pathway regulation (1) Trip1 none 0.22 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Trip1 Decreased ERK phosphorylation after EGF stimulation -3.3 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Trip1 none -0.08 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Trip1 none 0.73 30 minutes sSpitz stimulation 22028469

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