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Gene : Spx D. melanogaster

DB identifier  ? FBgn0015818 Secondary Identifier  ? CG3780
Name  ? Spliceosomal protein on the X Source  FlyBase
  • synonyms:
  • FBgn0015818,
  • FBan0003780,
  • SPX,
  • CG3780

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5 Alleles

DB identifier Symbol Allele Class Organism
FBal0287529 Spx[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0208614 Spx[GD11072]   Drosophila melanogaster
FBal0216653 Spx[HP10350]   Drosophila melanogaster
FBal0235444 Spx[KK108243]   Drosophila melanogaster
FBal0273955 Spx[NIG.3780R]   Drosophila melanogaster

39 Clones

Secondary Identifier DB identifier
EK130058 FBcl0085670
EN12811 FBcl0097815
EN01819 FBcl0097819
LD06767 FBcl0159677
RE19753 FBcl0193077
RE70733 FBcl0193234
RE48939 FBcl0193297
RE48337 FBcl0193919
RE44220 FBcl0193938
RE50839 FBcl0209761
RE72283 FBcl0225555
RE02924 FBcl0226042
RP003217802 FBcl0492664
RP003040256 FBcl0492665
RP003375790 FBcl0492666
RP003403948 FBcl0492667
RP003164001 FBcl0492668
RP003371264 FBcl0492669
RP003192095 FBcl0492670
RP003296946 FBcl0492671
RP003350160 FBcl0492672
RP003050925 FBcl0492673
RP003154601 FBcl0492674
RP003246382 FBcl0492675
RP003121236 FBcl0492676
RP003464635 FBcl0492677
RP003153078 FBcl0492678
RP003308837 FBcl0492679
RP003308263 FBcl0492680
RP003635703 FBcl0492681

3 Exons

DB identifier Symbol
FBgn0015818:1 Spx:1
FBgn0015818:2 Spx:2
FBgn0015818:3 Spx:3

1 Transcripts

DB identifier Gene
FBtr0070894 Spx

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0070894-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0070894-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
31558 NCBI Entrez Gene identifiers FBgn0015818
58050 BioGRID FBgn0015818

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 858.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1046.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 822.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 862.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 597.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 940.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 935.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1491.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 529.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 754.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 656.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 527.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 699.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 940.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 942.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 839.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 931.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 478.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 820.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 609.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 809.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 962.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 831.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 755.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 532.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1507.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1780.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1436.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1326.0
FBgn0015818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 938.0

2 Introns

DB identifier
Organism . Name
intron_FBgn0015818:1_FBgn0015818:2 Drosophila melanogaster
intron_FBgn0015818:2_FBgn0015818:3 Drosophila melanogaster

32 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Spx Decreased lipid droplet area -1.868381717   19067489
Lipid storage Spx Decreased lipid droplet area -3.655202203   19067489
Cytokinesis regulation Spx Binucleate cells with microtubule extensions weak   15547975
Alternative splicing Spx none sp   15492211
Intracellular Listeria monocytogenes infection Spx Increased GFP protein expression moderate   16020693
Constitutive protein secretion and Golgi organization (1) Spx Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Spx Decreased G1 DNA content, increased cytokinesis sp   16496002
Cell size and cell-cycle regulation (2) Spx none 1.088   16496002
Cell size and cell-cycle regulation (3) Spx none 489   16496002
Muscle morphogenesis and function (1) Spx Lethal np   20220848
Muscle morphogenesis and function (1) Spx Lethal np   20220848
Muscle morphogenesis and function (3) Spx none np   20220848
Heat nociception (1) Spx Developmentally lethal 0   21074052
Heart development and function (1) Spx none 0.88   20371351
Heart development and function (2) Spx Decreased viability 4.3   20371351
Serratia marcescens infection (1) Spx none -0.25   19520911
Notch pathway regulation (4) Spx Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) Spx Completely lethal (before pupal) sp   19363474
Self-renewal and differentiation in neural stem cells Spx GFP aggregates number, GFP aggregates size, neuroblast larger cell size, neuroblast less large cells, neuroblast cell shape, ganglion mother cell shorter lineages, neuroblast loss, neuroblast loss with larger neuroblast cell size, neuroblast underprolifer sp   21549331
Self-renewal and differentiation in neural stem cells Spx GFP aggregates number, GFP aggregates size, neuroblast larger cell size, neuroblast less large cells, neuroblast cell shape, ganglion mother cell shorter lineages, ganglion mother cell shape, neuroblast loss, neuroblast loss with larger neuroblast cell si sp   21549331
Notch pathway regulation (1) Spx Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) Spx Lethal strong en-GAL4 20493818
Notch pathway regulation (2) Spx none np C96-GAL4 20493818
Notch pathway regulation (2) Spx none np en-GAL4 20493818
Notch pathway regulation (3) Spx Upregulation of Notch pathway np   20493818
Adiposity regulation (1) Spx none -0.158   20074523
RTK-Ras-ERK pathway regulation (1) Spx none -0.17 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Spx none -0.08 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Spx Decreased ERK phosphorylation after sSpitz and EGF stimulation -1.87 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Spx none -1.26 30 minutes sSpitz stimulation 22028469

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