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Gene : RpS21 D. melanogaster

DB identifier  ? FBgn0015521 Secondary Identifier  ? CG2986
Name  ? Ribosomal protein S21 Source  FlyBase
  • synonyms:
  • CG2986,
  • l(2)k16814,
  • l(2)168/14,
  • Rp S21,
  • FBgn0014276,
  • FBgn0015521,
  • overgrown hematopoietic organs at 23B,
  • FBgn0010545,
  • l(2)03575,
  • M(2)23B,
  • overgrown hematopoietic organs 23B,
  • FBan0002986,
  • RpS21,
  • Ribosomal protein S21,
  • oho23,
  • oho23B,
  • overgrown hematopoietic organs-23

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12 Alleles

DB identifier Symbol Allele Class Organism
FBal0286819 RpS21[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286820 RpS21[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0096733 RpS21[R7]   Drosophila melanogaster
FBal0210250 RpS21[GD13670]   Drosophila melanogaster
FBal0044228 RpS21[1]   Drosophila melanogaster
FBal0096732 RpS21[R8]   Drosophila melanogaster
FBal0096735 RpS21[+t2.8]   Drosophila melanogaster
FBal0043430 RpS21[k16804a]   Drosophila melanogaster
FBal0035096 RpS21[k16814] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0096734 RpS21[R12]   Drosophila melanogaster
FBal0236039 RpS21[KK109086]   Drosophila melanogaster
FBal0008031 RpS21[03575]   Drosophila melanogaster

277 Clones

Secondary Identifier DB identifier
DPiM_RH57501 FBcl0741860
ESG0114a.B21_E12 FBcl0007131
ESG0115c.B21_B04 FBcl0007575
EC34605 FBcl0060765
EC22511 FBcl0060767
EC24591 FBcl0060773
EC00801 FBcl0072975
EC31489 FBcl0072977
EC01337 FBcl0072983
EC01037 FBcl0072985
EC00401 FBcl0072991
EC00179 FBcl0072995
EC00279 FBcl0072997
EP21535 FBcl0089147
EP08921 FBcl0089187
EN11506 FBcl0090205
EN11462 FBcl0090207
EN06359 FBcl0090209
EN16450 FBcl0101271
EN14222 FBcl0101497
EN04618 FBcl0101717
EN12033 FBcl0101719
EK069655 FBcl0106662
EK198520 FBcl0107316
EK063104 FBcl0107390
EK223805 FBcl0107422
EK178843 FBcl0107506
EK056845 FBcl0107670
EK261028 FBcl0107682
EK213347 FBcl0107690

10 Exons

DB identifier Symbol
FBgn0015521:2 RpS21:2
FBgn0015521:4 RpS21:4
FBgn0015521:5 RpS21:5
FBgn0015521:8 RpS21:8
FBgn0015521:7 RpS21:7
FBgn0015521:10 RpS21:10
FBgn0015521:1 RpS21:1
FBgn0015521:6 RpS21:6
FBgn0015521:3 RpS21:3
FBgn0015521:9 RpS21:9

5 Transcripts

DB identifier Gene
FBtr0335131 RpS21
FBtr0077621 RpS21
FBtr0077623 RpS21
FBtr0077622 RpS21
FBtr0273293 RpS21

10 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0335131-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0077621-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0077623-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0273293-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0077622-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0335131-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0077621-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0077623-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0273293-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0077622-3-prime-utr Drosophila melanogaster

Interactions

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52 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
33487 NCBI Entrez Gene identifiers FBgn0015521
59710 BioGRID FBgn0015521

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 9385.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 4422.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 11590.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 12581.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 5629.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 18993.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 6943.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 12289.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 20241.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 7910.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 8723.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 13162.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 9763.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 14864.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 17672.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 12239.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 8719.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 8661.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 13007.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 4272.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 10894.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 6812.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 5572.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 4802.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 4364.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 7896.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 7673.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 7112.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 6985.0
FBgn0015521 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 4249.0

10 Introns

DB identifier
Organism . Name
intron_FBgn0015521:1_FBgn0015521:4 Drosophila melanogaster
intron_FBgn0015521:4_FBgn0015521:6 Drosophila melanogaster
intron_FBgn0015521:2_FBgn0015521:4 Drosophila melanogaster
intron_FBgn0015521:4_FBgn0015521:5 Drosophila melanogaster
intron_FBgn0015521:5_FBgn0015521:9 Drosophila melanogaster
intron_FBgn0015521:5_FBgn0015521:8 Drosophila melanogaster
intron_FBgn0015521:5_FBgn0015521:7 Drosophila melanogaster
intron_FBgn0015521:7_FBgn0015521:10 Drosophila melanogaster
intron_FBgn0015521:2_FBgn0015521:3 Drosophila melanogaster
intron_FBgn0015521:3_FBgn0015521:5 Drosophila melanogaster

26 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage RpS21 none 0.994821458   19067489
Lipid storage RpS21 none -0.071739528   19067489
ERK signaling RpS21 ERK activation reduced weak   17086199
Intracellular Listeria monocytogenes infection RpS21 Increased GFP protein expression moderate   16020693
Hedgehog signaling RpS21 Decreased Hedgehog reporter activity -2.24   16311596
Constitutive protein secretion and Golgi organization (1) RpS21 Decreased horseradish peroxidase protein expression sp   16452979
Muscle morphogenesis and function (1) RpS21 Lethal np   20220848
Muscle morphogenesis and function (1) RpS21 Lethal np   20220848
Muscle morphogenesis and function (2) RpS21 Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Muscle morphogenesis and function (3) RpS21 none np   20220848
Heat nociception (1) RpS21 Developmentally lethal 0.12   21074052
Heat nociception (1) RpS21 none -1.17   21074052
Heart development and function (1) RpS21 Adult lethal 0.4   20371351
Heart development and function (1) RpS21 Embryonic lethal or no offspring 0.5   20371351
Heart development and function (2) RpS21 Decreased viability 4.45   20371351
Serratia marcescens infection (1) RpS21 none 0.766233766233766   19520911
Notch pathway regulation (4) RpS21 Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) RpS21 Completely lethal (before pupal) sp   19363474
Hh pathway regulation RpS21 Downregulation of Hh pathway -0.427701652349397   17903264
Hh pathway regulation RpS21 Downregulation of Hh pathway -0.388101608236082   17903264
Adiposity regulation (1) RpS21 none -0.492   20074523
RTK-Ras-ERK pathway regulation (1) RpS21 Decreased ERK phosphorylation after EGF stimulation -3.3 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) RpS21 none -0.94 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) RpS21 none -0 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) RpS21 Increased ERK phosphorylation after sSpitz and EGF stimulation 2.21 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation RpS21 none -0.84   23263283

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