Genomics
Gene Ontology Displayer
Homologue Displayer
Mod Mine G Browse Displayer
Overlapping Features Displayer
Regulatory Regions Displayer
9 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0134152 | Shc[KG06847] | Drosophila melanogaster | |
| FBal0147419 | Shc[+tEa] | Drosophila melanogaster | |
| FBal0181550 | Shc[13G] | Drosophila melanogaster | |
| FBal0141419 | Shc[SL20] | Drosophila melanogaster | |
| FBal0105104 | Shc[BG] | Drosophila melanogaster | |
| FBal0105105 | Shc[111-40] | amorphic allele - genetic evidence | Drosophila melanogaster |
| FBal0208530 | Shc[GD11053] | Drosophila melanogaster | |
| FBal0230798 | Shc[KK100514] | Drosophila melanogaster | |
| FBal0273927 | Shc[NIG.3715R] | Drosophila melanogaster |
35 Clones
2 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0076458-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0076458-3-prime-utr | Drosophila melanogaster |
Other
18 Pathways
- SHC-mediated cascade,
- Signaling by EGFR in Cancer,
- Downstream signaling of activated FGFR,
- Signaling by FGFR,
- Disease,
- Signaling by constitutively active EGFR,
- Activation of Chaperone Genes by XBP1(S),
- Metabolism of proteins,
- Signaling by ERBB2,
- Integrin alphaIIb beta3 signaling,
- Platelet Aggregation (Plug Formation),
- Unfolded Protein Response,
- Hemostasis,
- Platelet activation, signaling and aggregation,
- Signaling Pathways,
- Signaling by FGFR in disease,
- Activation of Chaperones by IRE1alpha,
- SHC1 events in ERBB2 signaling
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 44052 | NCBI Entrez Gene identifiers | FBgn0015296 |
| 68802 | BioGRID | FBgn0015296 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
19 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | Shc | none | -0.004043838 | 19067489 | |
| Lipid storage | Shc | none | 0.488906008 | 19067489 | |
| Heat nociception (1) | Shc | none | -1.17 | 21074052 | |
| Heart development and function (1) | Shc | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | Shc | none | 0.577319587628865 | 19520911 | |
| Serratia marcescens infection (1) | Shc | none | 0.705882352941176 | 19520911 | |
| Serratia marcescens infection (1) | Shc | none | 1.26136363636363 | 19520911 | |
| Notch pathway regulation (4) | Shc | none | 0 | 19363474 | |
| Notch induced transcription | Shc | none | 2.0052 | without Notch stimulation | 20959007 |
| Notch induced transcription | Shc | Upregulation of Notch pathway after Notch stimulation | 4.3372 | N(delta)ecn Notch stimulation | 20959007 |
| Notch induced transcription | Shc | none | 0.52018 | N(delta)ecn Notch stimulation | 20959007 |
| Adiposity regulation (1) | Shc | none | -0.285 | 20074523 | |
| Adiposity regulation (1) | Shc | none | 0.202 | 20074523 | |
| RTK-Ras-ERK pathway regulation (1) | Shc | Decreased ERK phosphorylation after EGF stimulation | -1.61 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | Shc | none | -0.25 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | Shc | none | -1.48 | 30 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | Shc | none | -1.14 | 10 minutes sSpitz stimulation | 22028469 |
| Hippo pathway regulation | Shc | none | 1.05 | 23263283 | |
| Glycosylation regulation (1) | Shc | none | sp | 21203496 |
