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Gene : heph D. melanogaster

DB identifier  ? FBgn0011224 Secondary Identifier  ? CG31000
Name  ? hephaestus Source  FlyBase
  • synonyms:
  • l(3)03429,
  • CG2290,
  • Hephaestus,
  • FBgn0010798,
  • FBgn0011433,
  • FBgn0051000,
  • Polypyrimidine Tract Binding protein,
  • FBan0031000,
  • ema,
  • polypyrimidine tract-binding protein,
  • ectopic margin,
  • HEPH,
  • l(3)j11B9,
  • FBgn0029138,
  • CG31000,
  • FBgn0011224,
  • dmPTB,
  • CG2094,
  • PTB,
  • FBgn0039885,
  • FBgn0039884,
  • dPTB

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123 Alleles

DB identifier Symbol Allele Class Organism
FBal0283418 heph[MI03453]   Drosophila melanogaster
FBal0220730 heph[JF02366]   Drosophila melanogaster
FBal0265992 heph[ex3.4]   Drosophila melanogaster
FBal0267279 heph[MI04855]   Drosophila melanogaster
FBal0282002 heph[9.189]   Drosophila melanogaster
FBal0282003 heph[18.104]   Drosophila melanogaster
FBal0211781 heph[CC00664]   Drosophila melanogaster
FBal0179533 heph[W18]   Drosophila melanogaster
FBal0179534 heph[DG10602]   Drosophila melanogaster
FBal0179496 heph[d10112]   Drosophila melanogaster
FBal0179498 heph[d06469]   Drosophila melanogaster
FBal0179500 heph[d05770]   Drosophila melanogaster
FBal0179501 heph[d05596]   Drosophila melanogaster
FBal0179504 heph[d01420]   Drosophila melanogaster
FBal0179505 heph[d01137]   Drosophila melanogaster
FBal0179480 heph[f07076]   Drosophila melanogaster
FBal0179482 heph[f05053]   Drosophila melanogaster
FBal0179487 heph[f01245]   Drosophila melanogaster
FBal0179493 heph[e01647]   Drosophila melanogaster
FBal0179494 heph[e00963]   Drosophila melanogaster
FBal0179506 heph[c07125]   Drosophila melanogaster
FBal0179507 heph[c06824]   Drosophila melanogaster
FBal0179508 heph[c06244]   Drosophila melanogaster
FBal0179509 heph[c05593]   Drosophila melanogaster
FBal0179511 heph[c05368]   Drosophila melanogaster
FBal0179512 heph[c04692]   Drosophila melanogaster
FBal0179513 heph[c01827]   Drosophila melanogaster
FBal0179518 heph[c01512]   Drosophila melanogaster
FBal0179516 heph[c01551]   Drosophila melanogaster
FBal0179514 heph[c01635]   Drosophila melanogaster

244 Clones

Secondary Identifier DB identifier
EK111933 FBcl0002302
EK308245 FBcl0002312
EK062752 FBcl0002330
EK279116 FBcl0002390
EK110026 FBcl0002478
EK094856 FBcl0002486
EK301646 FBcl0002496
EK193153 FBcl0002504
EK031006 FBcl0002516
EK115531 FBcl0002526
EK115537 FBcl0002542
EK071825 FBcl0002552
EK061807 FBcl0002578
EK236026 FBcl0002586
EK149108 FBcl0002624
EK215242 FBcl0002634
EK171219 FBcl0002642
EK067663 FBcl0002652
EK051618 FBcl0002674
EK165338 FBcl0002682
EK090715 FBcl0002690
EK170064 FBcl0002702
EK148608 FBcl0002712
EK231315 FBcl0002730
EK019007 FBcl0002740
EK139237 FBcl0002750
EK069746 FBcl0002768
EK190808 FBcl0002790
EK131158 FBcl0002816
EK182743 FBcl0002836

44 Exons

DB identifier Symbol
FBgn0011224:28 heph:28
FBgn0011224:26 heph:26
FBgn0011224:36 heph:36
FBgn0011224:32 heph:32
FBgn0011224:15 heph:15
FBgn0011224:14 heph:14
FBgn0011224:13 heph:13
FBgn0011224:11 heph:11
FBgn0011224:10 heph:10
FBgn0011224:9 heph:9
FBgn0011224:8 heph:8
FBgn0011224:7 heph:7
FBgn0011224:6 heph:6
FBgn0011224:4 heph:4
FBgn0011224:33 heph:33
FBgn0011224:31 heph:31
FBgn0011224:39 heph:39
FBgn0011224:27 heph:27
FBgn0011224:21 heph:21
FBgn0011224:19 heph:19
FBgn0011224:18 heph:18
FBgn0011224:3 heph:3
FBgn0011224:37 heph:37
FBgn0011224:42 heph:42
FBgn0011224:43 heph:43
FBgn0011224:41 heph:41
FBgn0011224:30 heph:30
FBgn0011224:29 heph:29
FBgn0011224:44 heph:44
FBgn0011224:5 heph:5

24 Transcripts

DB identifier Gene
FBtr0306692 heph
FBtr0085887 heph
FBtr0306693 heph
FBtr0085884 heph
FBtr0300263 heph
FBtr0112864 heph
FBtr0300266 heph
FBtr0112866 heph
FBtr0085881 heph
FBtr0085878 heph
FBtr0300264 heph
FBtr0085886 heph
FBtr0085885 heph
FBtr0085888 heph
FBtr0085879 heph
FBtr0085883 heph
FBtr0085882 heph
FBtr0112865 heph
FBtr0300270 heph
FBtr0300267 heph
FBtr0085880 heph
FBtr0300268 heph
FBtr0300269 heph
FBtr0300265 heph

48 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0085887-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0085888-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0085879-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0085880-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0085881-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0085882-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0085883-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0085884-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0085885-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0085886-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0085878-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0112864-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0112865-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0112866-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300263-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300264-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300265-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300266-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300267-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300268-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300269-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300270-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0306692-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0306693-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0085887-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0085888-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0085879-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0085880-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0085881-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0085882-3-prime-utr Drosophila melanogaster

Interactions

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
48571 NCBI Entrez Gene identifiers FBgn0011224
71508 BioGRID FBgn0011224

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1615.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2772.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 440.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 435.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 727.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 755.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 388.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 752.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 952.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 868.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 482.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 999.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 379.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1723.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 759.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 519.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1205.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 404.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 719.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 692.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 678.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 3748.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 513.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 480.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 481.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 4197.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 4274.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1994.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1927.0
FBgn0011224 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1556.0

59 Introns

DB identifier
Organism . Name
intron_FBgn0011224:36_FBgn0011224:32 Drosophila melanogaster
intron_FBgn0011224:32_FBgn0011224:28 Drosophila melanogaster
intron_FBgn0011224:28_FBgn0011224:26 Drosophila melanogaster
intron_FBgn0011224:26_FBgn0011224:15 Drosophila melanogaster
intron_FBgn0011224:15_FBgn0011224:14 Drosophila melanogaster
intron_FBgn0011224:14_FBgn0011224:13 Drosophila melanogaster
intron_FBgn0011224:13_FBgn0011224:11 Drosophila melanogaster
intron_FBgn0011224:11_FBgn0011224:10 Drosophila melanogaster
intron_FBgn0011224:10_FBgn0011224:9 Drosophila melanogaster
intron_FBgn0011224:9_FBgn0011224:8 Drosophila melanogaster
intron_FBgn0011224:8_FBgn0011224:7 Drosophila melanogaster
intron_FBgn0011224:7_FBgn0011224:6 Drosophila melanogaster
intron_FBgn0011224:6_FBgn0011224:4 Drosophila melanogaster
intron_FBgn0011224:33_FBgn0011224:32 Drosophila melanogaster
intron_FBgn0011224:32_FBgn0011224:31 Drosophila melanogaster
intron_FBgn0011224:31_FBgn0011224:26 Drosophila melanogaster
intron_FBgn0011224:21_FBgn0011224:19 Drosophila melanogaster
intron_FBgn0011224:19_FBgn0011224:15 Drosophila melanogaster
intron_FBgn0011224:42_FBgn0011224:37 Drosophila melanogaster
intron_FBgn0011224:37_FBgn0011224:32 Drosophila melanogaster
intron_FBgn0011224:32_FBgn0011224:27 Drosophila melanogaster
intron_FBgn0011224:27_FBgn0011224:26 Drosophila melanogaster
intron_FBgn0011224:26_FBgn0011224:18 Drosophila melanogaster
intron_FBgn0011224:18_FBgn0011224:15 Drosophila melanogaster
intron_FBgn0011224:6_FBgn0011224:3 Drosophila melanogaster
intron_FBgn0011224:44_FBgn0011224:32 Drosophila melanogaster
intron_FBgn0011224:6_FBgn0011224:5 Drosophila melanogaster
intron_FBgn0011224:42_FBgn0011224:38 Drosophila melanogaster
intron_FBgn0011224:38_FBgn0011224:32 Drosophila melanogaster
intron_FBgn0011224:35_FBgn0011224:32 Drosophila melanogaster

32 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage heph none -0.234818547   19067489
Lipid storage heph none -0.164618594   19067489
Lipid storage heph none 0.850491468   19067489
Lipid storage heph none 0.059935253   19067489
Lipid storage heph none 1.527851514   19067489
Lipid storage heph none 0.901031795   19067489
Lipid storage heph none -0.215875746   19067489
Lipid storage heph none 0.538882303   19067489
ERK signaling heph ERK activation reduced weak   17086199
Alternative splicing heph none sp   15492211
Cell size and cell-cycle regulation (1) heph none sp   16496002
Muscle morphogenesis and function (1) heph none np   20220848
Muscle morphogenesis and function (1) heph none np   20220848
Heat nociception (1) heph none 0.83   21074052
Heat nociception (1) heph none -0.84   21074052
Heart development and function (1) heph none 1   20371351
Heart development and function (1) heph none 1   20371351
Serratia marcescens infection (1) heph none -0.574803149606299   19520911
Notch pathway regulation (4) heph Bristle morphology defects, notum malformation death sp   19363474
Notch pathway regulation (4) heph Notum malformation death 3   19363474
Notch induced transcription heph Downregulation of Notch pathway after Notch stimulation -3.0496 N(delta)ecn Notch stimulation 20959007
Notch induced transcription heph none -1.2657 N(delta)ecn Notch stimulation 20959007
Notch induced transcription heph none -1.8933 without Notch stimulation 20959007
Pol II elongation heph none 98 20 min heat shock 19279664
Adiposity regulation (1) heph none -0.311   20074523
RTK-Ras-ERK pathway regulation (1) heph none -0.01 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) heph Decreased ERK phosphorylation after EGF stimulation -1.83 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) heph none -0.37 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) heph none 0.37 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation heph none -0.5   23263283

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