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Gene : TfIIFalpha D. melanogaster

DB identifier  ? FBgn0010282 Secondary Identifier  ? CG10281
Name  ? Transcription factor IIFalpha Source  FlyBase
  • synonyms:
  • large subunit of transcription factor 5,
  • factor 5a,
  • FBgn0010282,
  • TFIIF-L,
  • RAP74,
  • F5a,
  • DmTFIIF,
  • FBan0010281,
  • CG10281,
  • factor 5,
  • TFIIF,
  • FBgn0010281,
  • TFIIFalpha,
  • TFIIFa,
  • TFIIF large subunit,
  • 154355_at

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5 Alleles

DB identifier Symbol Allele Class Organism
FBal0181281 TfIIFalpha[d01485]   Drosophila melanogaster
FBal0259238 TfIIFalpha[KK102868]   Drosophila melanogaster
FBal0270408 TfIIFalpha[NIG.10281R]   Drosophila melanogaster
FBal0262818 TfIIFalpha[GL00352]   Drosophila melanogaster
FBal0208768 TfIIFalpha[GD4143]   Drosophila melanogaster

82 Clones

Secondary Identifier DB identifier
EK143125 FBcl0026698
EK198353 FBcl0026712
EK028159 FBcl0026728
GH09928 FBcl0125029
GM02833 FBcl0137991
GM22745 FBcl0144141
LD33679 FBcl0173574
LD26157 FBcl0173575
LD28729 FBcl0173590
LP12524 FBcl0187419
RE59463 FBcl0222896
RE37378 FBcl0222954
RE23985 FBcl0223037
RE01951 FBcl0223043
RE58201 FBcl0223104
RE03968 FBcl0223120
RH45982 FBcl0263630
Dmel_dig_013265_0663_1877 FBcl0367923
Dmel_neb_010883_0896_0682 FBcl0367932
FGH102G01 FBcl0386764
FGH111H08 FBcl0387434
FGM103D03 FBcl0389242
RP003278904 FBcl0520267
RP003594729 FBcl0520266
RP003486707 FBcl0520249
RP003055948 FBcl0520250
RP003200750 FBcl0520251
RP003323499 FBcl0520252
RP003260755 FBcl0520253
RP003305349 FBcl0520254

4 Exons

DB identifier Symbol
FBgn0010282:1 TfIIFalpha:1
FBgn0010282:2 TfIIFalpha:2
FBgn0010282:3 TfIIFalpha:3
FBgn0010282:4 TfIIFalpha:4

1 Transcripts

DB identifier Gene
FBtr0081719 TfIIFalpha

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0081719-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0081719-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
40790 NCBI Entrez Gene identifiers FBgn0010282
65991 BioGRID FBgn0010282

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1367.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1326.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 974.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1257.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1271.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1254.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 952.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1350.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 835.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1113.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1038.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 991.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1412.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1000.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 940.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 990.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1077.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1663.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 959.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1086.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 771.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1314.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1153.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1347.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1157.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3131.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 3343.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2950.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1242.0
FBgn0010282 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1176.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0010282:1_FBgn0010282:2 Drosophila melanogaster
intron_FBgn0010282:2_FBgn0010282:3 Drosophila melanogaster
intron_FBgn0010282:3_FBgn0010282:4 Drosophila melanogaster

19 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage TfIIFalpha none 0.125760624   19067489
Lipid storage TfIIFalpha none -0.017369488   19067489
ERK signaling TfIIFalpha ERK activation increased strong   17086199
Constitutive protein secretion and Golgi organization (1) TfIIFalpha Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) TfIIFalpha none sp   16496002
Dendrite pattern formation TfIIFalpha none np   16547170
Combinatorial effect with methyl methanesulphonate (1) TfIIFalpha none sp   19543366
Mutant human huntingtin aggregation TfIIFalpha Decreased mutant human huntingtin aggregation <= -2   19789644
Heat nociception (1) TfIIFalpha Developmentally lethal 0   21074052
Heart development and function (1) TfIIFalpha none 1   20371351
PGN-induced dJNK phosphorylation TfIIFalpha Increased P-JNK protein expression with PGN 2.11 60 min PGN induction 19893628
Self-renewal and differentiation in neural stem cells TfIIFalpha GFP aggregates number, GFP aggregates size, neuroblast cell shape, ganglion mother cell larger cell size, ganglion mother cell shorter lineages, ganglion mother cell shape, neuroblast underproliferation, lethal sp   21549331
Pol II elongation TfIIFalpha Decreased Hsp70 mRNA expression 39 20 min heat shock 19279664
RTK-Ras-ERK pathway regulation (1) TfIIFalpha none -0.91 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) TfIIFalpha none 0.8 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) TfIIFalpha none 0.6 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) TfIIFalpha Increased ERK phosphorylation after sSpitz and EGF stimulation 1.58 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation TfIIFalpha none -0.91   23263283
Glycosylation regulation (1) TfIIFalpha none sp   21203496

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