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Gene : alpha-Cat D. melanogaster

DB identifier  ? FBgn0010215 Secondary Identifier  ? CG17947
Name  ? alpha Catenin Source  FlyBase
  • synonyms:
  • Dalphacat,
  • alpha-ctn,
  • Dalpha-cadherin,
  • CT39986,
  • Dalpha-Cat,
  • Dmcatp,
  • a-catenin,
  • a-Cat,
  • FBgn0010215,
  • alpha-CAT,
  • DalphaC,
  • D-alpha-catenin,
  • Dalpha-Catenin,
  • CG17947,
  • alphaCatenin,
  • DalphaCatenin,
  • FBan0017947,
  • alpha-Catenin,
  • alphaCAT,
  • LD30423p,
  • alpha Catenin

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17 Alleles

DB identifier Symbol Allele Class Organism
FBal0282554 alpha-Cat[1.dsRNA.Scer\UAS]   Drosophila melanogaster
FBal0282555 alpha-Cat[3.dsRNA.Scer\UAS]   Drosophila melanogaster
FBal0257207 alpha-Cat[HMS00317]   Drosophila melanogaster
FBal0260363 alpha-Cat[MI02577]   Drosophila melanogaster
FBal0278548 alpha-Cat[GL00636]   Drosophila melanogaster
FBal0286106 alpha-Cat[MI09241]   Drosophila melanogaster
FBal0261838 alpha-Cat[CPTI002342]   Drosophila melanogaster
FBal0261839 alpha-Cat[CPTI002516]   Drosophila melanogaster
FBal0141970 alpha-Cat[cMa]   Drosophila melanogaster
FBal0145257 alpha-Cat[dsRNA.cYa]   Drosophila melanogaster
FBal0141971 alpha-Cat[a.cMa]   Drosophila melanogaster
FBal0095916 alpha-Cat[Scer\UAS.T:Avic\GFP-sg]   Drosophila melanogaster
FBal0141972 alpha-Cat[Scer\UAS.P\T.cMa]   Drosophila melanogaster
FBal0198530 alpha-Cat[GD8808]   Drosophila melanogaster
FBal0279019 alpha-Cat[HMS01903]   Drosophila melanogaster
FBal0235251 alpha-Cat[KK107916]   Drosophila melanogaster
FBal0279996 alpha-Cat[Scer\UAS.T:Zzzz\eqFP578-TagRFP-T]   Drosophila melanogaster

113 Clones

Secondary Identifier DB identifier
EK150052 FBcl0068418
EK053206 FBcl0068426
EK184434 FBcl0068432
EK255710 FBcl0069254
EK279356 FBcl0069308
EK263160 FBcl0069362
EK159003 FBcl0069366
EK210046 FBcl0069374
EK148719 FBcl0069390
EK226034 FBcl0069402
EK147135 FBcl0069482
EK104520 FBcl0069522
EK156323 FBcl0069582
EK104459 FBcl0069628
EK261937 FBcl0069654
EN16342 FBcl0097131
EN06009 FBcl0097133
GH22876 FBcl0111939
GM02796 FBcl0141939
LD04577 FBcl0154226
LD14106 FBcl0154227
LD05188 FBcl0154228
LD07667 FBcl0154229
LD20893 FBcl0154230
LD15926 FBcl0154231
LD18130 FBcl0154233
LD14569 FBcl0154234
LD20701 FBcl0154236
LD07464 FBcl0154238
LD18254 FBcl0154239

13 Exons

DB identifier Symbol
FBgn0010215:13 alpha-Cat:13
FBgn0010215:12 alpha-Cat:12
FBgn0010215:11 alpha-Cat:11
FBgn0010215:10 alpha-Cat:10
FBgn0010215:8 alpha-Cat:8
FBgn0010215:7 alpha-Cat:7
FBgn0010215:6 alpha-Cat:6
FBgn0010215:5 alpha-Cat:5
FBgn0010215:4 alpha-Cat:4
FBgn0010215:3 alpha-Cat:3
FBgn0010215:2 alpha-Cat:2
FBgn0010215:1 alpha-Cat:1
FBgn0010215:9 alpha-Cat:9

2 Transcripts

DB identifier Gene
FBtr0339894 alpha-Cat
FBtr0070038 alpha-Cat

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0070038-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0339894-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0070038-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0339894-3-prime-utr Drosophila melanogaster

Interactions

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0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
40517 NCBI Entrez Gene identifiers FBgn0010215
65744 BioGRID FBgn0010215

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from UniProt  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1778.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1592.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1673.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1678.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1982.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1136.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1495.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1005.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 895.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1680.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1607.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1485.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1406.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 886.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1812.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1149.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2009.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1196.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1362.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 2131.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 995.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1498.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1432.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1696.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1751.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3201.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 3188.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 3514.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2274.0
FBgn0010215 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 2377.0

13 Introns

DB identifier
Organism . Name
intron_FBgn0010215:13_FBgn0010215:12 Drosophila melanogaster
intron_FBgn0010215:12_FBgn0010215:11 Drosophila melanogaster
intron_FBgn0010215:11_FBgn0010215:9 Drosophila melanogaster
intron_FBgn0010215:9_FBgn0010215:7 Drosophila melanogaster
intron_FBgn0010215:7_FBgn0010215:6 Drosophila melanogaster
intron_FBgn0010215:6_FBgn0010215:5 Drosophila melanogaster
intron_FBgn0010215:5_FBgn0010215:4 Drosophila melanogaster
intron_FBgn0010215:4_FBgn0010215:3 Drosophila melanogaster
intron_FBgn0010215:3_FBgn0010215:2 Drosophila melanogaster
intron_FBgn0010215:2_FBgn0010215:1 Drosophila melanogaster
intron_FBgn0010215:11_FBgn0010215:10 Drosophila melanogaster
intron_FBgn0010215:10_FBgn0010215:8 Drosophila melanogaster
intron_FBgn0010215:8_FBgn0010215:7 Drosophila melanogaster

26 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage alpha-Cat Decreased lipid droplet area -1.785382203   19067489
Lipid storage alpha-Cat Decreased lipid droplet area -2.270707895   19067489
Lipid storage alpha-Cat Decreased lipid droplet area -1.493542574   19067489
Lipid storage alpha-Cat Decreased lipid droplet area 0.825558939   19067489
Lipid storage alpha-Cat Decreased lipid droplet area 0.336767255   19067489
Cell size and cell-cycle regulation (1) alpha-Cat none sp   16496002
Heart development and function alpha-Cat Heart tube assembly defects, heart patterning defects np   14684833
Muscle morphogenesis and function (1) alpha-Cat Lethal np   20220848
Muscle morphogenesis and function (1) alpha-Cat none np   20220848
Muscle morphogenesis and function (1) alpha-Cat none np   20220848
Heat nociception (1) alpha-Cat none -1.17   21074052
Heat nociception (1) alpha-Cat none -1.17   21074052
Heart development and function (1) alpha-Cat none 1   20371351
Serratia marcescens infection (1) alpha-Cat none -1.05882352941176   19520911
Notch pathway regulation (4) alpha-Cat Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) alpha-Cat Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) alpha-Cat Completely lethal (pupal) sp   19363474
PGN-induced dJNK phosphorylation alpha-Cat Increased P-JNK protein expression with PGN 2.39 60 min PGN induction 19893628
Adiposity regulation (1) alpha-Cat none -0.416   20074523
RTK-Ras-ERK pathway regulation (1) alpha-Cat Increased ERK phosphorylation after EGF stimulation 2 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) alpha-Cat none 0.02 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) alpha-Cat none -0.47 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) alpha-Cat none 0.05 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation alpha-Cat none 1.22   23263283
Muscle development and maintenance alpha-Cat Pupal lethal sp  
Muscle maintenance alpha-Cat none sp  

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