modENCODE |  Help |  blog

Gene : msl-2 D. melanogaster

DB identifier  ? FBgn0005616 Secondary Identifier  ? CG3241
Name  ? male-specific lethal 2 Source  FlyBase
  • synonyms:
  • Msl 1-3,
  • FBgn0002852,
  • killer-of-males-A,
  • MSL-2,
  • killer of males,
  • FBan0003241,
  • MSL2,
  • male specific-lethal 2,
  • male-specific-lethal 2,
  • FBgn0005616,
  • kmA,
  • male specifc lethal,
  • male-specific-lethal-2,
  • MSL,
  • male specific lethal 2,
  • km(2)A,
  • CG3241,
  • FBgn0001317

Sequence Feature Displayer

Publication Counts Displayer

Genomics

Gene Ontology Displayer

Homologue Displayer

Mod Mine G Browse Displayer

Overlapping Features Displayer

Regulatory Regions Displayer

82 Alleles

DB identifier Symbol Allele Class Organism
FBal0248832 msl-2[hs.T:Avic\GFP-Venus]   Drosophila melanogaster
FBal0268335 msl-2[Scer\UAS.P\T.cLa]   Drosophila melanogaster
FBal0283042 msl-2[HTB]   Drosophila melanogaster
FBal0285615 msl-2[hs.T:Scer\GAL4-DBD]   Drosophila melanogaster
FBal0285616 msl-2[hs.PS]   Drosophila melanogaster
FBal0245683 msl-2[JF01412]   Drosophila melanogaster
FBal0044202 msl-2[P17]   Drosophila melanogaster
FBal0044203 msl-2[P22]   Drosophila melanogaster
FBal0044204 msl-2[P4]   Drosophila melanogaster
FBal0137140 msl-2[KG06747]   Drosophila melanogaster
FBal0012562 msl-2[2]   Drosophila melanogaster
FBal0046132 msl-2[+t33.5]   Drosophila melanogaster
FBal0044192 msl-2[+t11.5]   Drosophila melanogaster
FBal0044193 msl-2[+t10]   Drosophila melanogaster
FBal0044194 msl-2[+t5.1]   Drosophila melanogaster
FBal0044196 msl-2[109-6.1]   Drosophila melanogaster
FBal0044197 msl-2[110-5.5]   Drosophila melanogaster
FBal0044198 msl-2[113-9]   Drosophila melanogaster
FBal0044199 msl-2[119-9.5]   Drosophila melanogaster
FBal0044200 msl-2[129-7.9]   Drosophila melanogaster
FBal0044201 msl-2[Hsp83.PK]   Drosophila melanogaster
FBal0046131 msl-2[+t11.0]   Drosophila melanogaster
FBal0046133 msl-2[+t5.0]   Drosophila melanogaster
FBal0061023 msl-2[tKf]   Drosophila melanogaster
FBal0061024 msl-2[tKe]   Drosophila melanogaster
FBal0061025 msl-2[tKd]   Drosophila melanogaster
FBal0061026 msl-2[tKc]   Drosophila melanogaster
FBal0061027 msl-2[SXB2]   Drosophila melanogaster
FBal0061028 msl-2[SXB1]   Drosophila melanogaster
FBal0061029 msl-2[SXB1-2]   Drosophila melanogaster

57 Clones

Secondary Identifier DB identifier
EK104645 FBcl0040574
EK249327 FBcl0040680
EK303903 FBcl0040692
EK161514 FBcl0040718
EK119028 FBcl0040732
EK122730 FBcl0040744
EK163656 FBcl0040758
EK051617 FBcl0040770
EK294743 FBcl0040794
EK237729 FBcl0040848
EK050217 FBcl0042346
EK199338 FBcl0042860
EK188062 FBcl0042908
EK052046 FBcl0043036
EK064045 FBcl0043060
EK183959 FBcl0043110
EK184112 FBcl0043122
EK184161 FBcl0043146
EK098632 FBcl0106010
GH22488 FBcl0134373
LD03176 FBcl0162186
RE24832 FBcl0235735
RE01106 FBcl0235747
RE31422 FBcl0236019
RE62637 FBcl0236044
RE20469 FBcl0236203
RH23787 FBcl0272086
RH64324 FBcl0272437
RH26553 FBcl0272506
SD08701 FBcl0291449

4 Exons

DB identifier Symbol
FBgn0005616:4 msl-2:4
FBgn0005616:2 msl-2:2
FBgn0005616:1 msl-2:1
FBgn0005616:3 msl-2:3

2 Transcripts

DB identifier Gene
FBtr0077570 msl-2
FBtr0077571 msl-2

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0077570-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0077571-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0077570-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0077571-3-prime-utr Drosophila melanogaster

Interactions

Cytoscape Network Displayer

 

Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
33565 NCBI Entrez Gene identifiers FBgn0005616
59776 BioGRID FBgn0005616

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 418.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 528.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 355.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 392.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 421.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 425.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1666.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 330.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1081.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 515.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 454.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 169.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 470.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 193.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2066.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 433.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1583.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 316.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1158.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 494.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2360.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 486.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 320.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 521.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 377.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 279.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 557.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 546.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 372.0
FBgn0005616 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 294.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0005616:4_FBgn0005616:2 Drosophila melanogaster
intron_FBgn0005616:2_FBgn0005616:1 Drosophila melanogaster
intron_FBgn0005616:3_FBgn0005616:1 Drosophila melanogaster

19 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage msl-2 none 0.66363501   19067489
Lipid storage msl-2 none -0.636127655   19067489
ERK signaling msl-2 ERK activation increased weak   17086199
Cell size and cell-cycle regulation (1) msl-2 none sp   16496002
Mitosis msl-2 Chromosome misalignment np   17412918
Muscle morphogenesis and function (1) msl-2 Weak flyer np   20220848
Muscle morphogenesis and function (2) msl-2 Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Heat nociception (1) msl-2 Increased noxious heat avoidance 3.95   21074052
Heart development and function (1) msl-2 none 1   20371351
Serratia marcescens infection (1) msl-2 none 1.04477611940298   19520911
Notch pathway regulation (4) msl-2 none 0   19363474
PGN-induced dJNK phosphorylation msl-2 Decreased P-JNK protein expression with PGN -3.47 15 min PGN induction 19893628
Adiposity regulation (1) msl-2 none -0.43   20074523
Secretory pathway regulation msl-2 Decreased BiP signal peptide and firefly luciferase fusion protein expression (-2) - (-1.5)   19942856
RTK-Ras-ERK pathway regulation (1) msl-2 none -0.24 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) msl-2 none 0.82 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) msl-2 none -0.33 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) msl-2 none 1.18 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation msl-2 none 1.06   23263283

0 Submissions