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Gene : R D. melanogaster

DB identifier  ? FBgn0004636 Secondary Identifier  ? CG1956
Name  ? Roughened Source  FlyBase
  • synonyms:
  • E(faf),
  • Dras62B,
  • BEST:GH18528,
  • FBgn0004636,
  • Ras3,
  • ras 3,
  • DRap1,
  • C-ras3,
  • DRap,
  • FBgn0003190,
  • Dras3,
  • FBgn0003207,
  • Rap1 GTPase,
  • Enhancer of faf,
  • l(3)62Bf,
  • P08645,
  • FCG-C,
  • FBgn0045818,
  • RasIII,
  • Rap,
  • l(3)R,
  • RAP1,
  • FBan0001956,
  • CG1956,
  • D-Rap1,
  • roughened,
  • R

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49 Alleles

DB identifier Symbol Allele Class Organism
FBal0192128 R[MB00790]   Drosophila melanogaster
FBal0276781 R[N17.hs2sev]   Drosophila melanogaster
FBal0276782 R[V12.hs2sev]   Drosophila melanogaster
FBal0259559 R[KK107785]   Drosophila melanogaster
FBal0137389 R[P5709] amorphic allele - genetic evidence Drosophila melanogaster
FBal0269539 R[S17A.Scer\UAS]   Drosophila melanogaster
FBal0267668 R[D25-4]   Drosophila melanogaster
FBal0083270 R[CD3]   Drosophila melanogaster
FBal0083269 R[GMR.PL]   Drosophila melanogaster
FBal0095628 R[hs.PA]   Drosophila melanogaster
FBal0095631 R[+t4.5]   Drosophila melanogaster
FBal0104053 R[W12]   Drosophila melanogaster
FBal0104050 R[W24]   Drosophila melanogaster
FBal0104055 R[A18]   Drosophila melanogaster
FBal0152269 R[CD5]   Drosophila melanogaster
FBal0104046 R[W31]   Drosophila melanogaster
FBal0104044 R[sev]   Drosophila melanogaster
FBal0104049 R[W27]   Drosophila melanogaster
FBal0042714 R[rvB1] amorphic allele - genetic evidence, loss of function allele Drosophila melanogaster
FBal0014168 R[1] neomorphic allele - genetic evidence Drosophila melanogaster
FBal0065999 R[E8]   Drosophila melanogaster
FBal0083267 R[unspecified] loss of function allele Drosophila melanogaster
FBal0156010 R[PIE-6]   Drosophila melanogaster
FBal0014169 R[2]   Drosophila melanogaster
FBal0104051 R[W21]   Drosophila melanogaster
FBal0104054 R[A3]   Drosophila melanogaster
FBal0030095 R[revG8] loss of function allele Drosophila melanogaster
FBal0066000 R[E127]   Drosophila melanogaster
FBal0014170 R[51b]   Drosophila melanogaster
FBal0104052 R[W13]   Drosophila melanogaster

110 Clones

Secondary Identifier DB identifier
DPiM_RE42418 FBcl0741232
ESG015a.E21_G07 FBcl0008601
EK259411 FBcl0060068
EK212352 FBcl0060120
EK157306 FBcl0061232
EK276157 FBcl0061310
EK171518 FBcl0061920
EK130232 FBcl0062012
EK160336 FBcl0062210
EK159412 FBcl0062662
EK120762 FBcl0062698
EK266354 FBcl0062736
EK114202 FBcl0062882
EK220537 FBcl0062938
EK173435 FBcl0063838
EK068446 FBcl0063918
EK190608 FBcl0063956
EK057840 FBcl0063988
EK016142 FBcl0064022
EK090559 FBcl0064682
EK064218 FBcl0064724
EK136532 FBcl0064800
EK127906 FBcl0064836
EK258513 FBcl0064874
EK127919 FBcl0064912
EK150650 FBcl0064946
EK075153 FBcl0065046
EK198060 FBcl0065434
EK254510 FBcl0065470
EK295853 FBcl0065542

4 Exons

DB identifier Symbol
FBgn0004636:4 R:4
FBgn0004636:1 R:1
FBgn0004636:3 R:3
FBgn0004636:2 R:2

3 Transcripts

DB identifier Gene
FBtr0072867 R
FBtr0303154 R
FBtr0332671 R

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0072867-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0303154-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0332671-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0072867-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0303154-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0332671-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
38244 NCBI Entrez Gene identifiers FBgn0004636
63773 BioGRID FBgn0004636

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1651.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1511.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 963.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1191.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1585.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1859.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1890.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1092.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 3221.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2288.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1922.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1057.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1366.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1265.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1645.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1294.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1870.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1594.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1729.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1627.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2423.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2171.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1418.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1656.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2199.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1671.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1846.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1950.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1745.0
FBgn0004636 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1512.0

2 Introns

DB identifier
Organism . Name
intron_FBgn0004636:3_FBgn0004636:1 Drosophila melanogaster
intron_FBgn0004636:4_FBgn0004636:1 Drosophila melanogaster

26 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage R none 0.059345567   19067489
Lipid storage R none 0.568405018   19067489
Cell morphology R Morphology np   14527345
Cell size and cell-cycle regulation (1) R none sp   16496002
Cell size and cell-cycle regulation (1) R none sp   16496002
Integrin adhesion R Round np   18166658
Microtubule assembly and organization R none np   18463163
Muscle morphogenesis and function (1) R Lethal np   20220848
Muscle morphogenesis and function (1) R none np   20220848
Heat nociception (1) R none -1.17   21074052
Heat nociception (1) R none -1.17   21074052
Heart development and function (1) R none 1   20371351
Serratia marcescens infection (1) R none -0.204545454545454   19520911
Notch pathway regulation (4) R Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) R Completely lethal (pupal) sp   19363474
Notch pathway regulation (1) R Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) R Lethal strong en-GAL4 20493818
Notch pathway regulation (2) R Downregulation of Notch pathway; wing disc NRE:EGFP: down; wing disc myrRFP: reduced; lethal sp en-GAL4 20493818
Notch pathway regulation (2) R Up- and downregulation of Notch pathway; adult wing margin: notches; wing pouch: spoon-like, crumbled sp C96-GAL4 20493818
Notch pathway regulation (3) R none np   20493818
Adiposity regulation (1) R none 0.016   20074523
RTK-Ras-ERK pathway regulation (1) R Decreased ERK phosphorylation after EGF stimulation -2.52 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) R none -1.35 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) R none 0.12 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) R none 0.46 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation R none 0.05   23263283

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