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Gene : T-cp1 D. melanogaster

DB identifier  ? FBgn0003676 Secondary Identifier  ? CG5374
Name  ? Tcp1-like Source  FlyBase
  • synonyms:
  • CG5374,
  • gh05123,
  • Tcp1-alpha,
  • FBgn0003676,
  • T-cpl,
  • Tcp-1,
  • TCP-1alpha,
  • TCPA_DROME,
  • CCT1,
  • T-complex 1,
  • Tcp1,
  • BEST:GH05123,
  • T-CP1,
  • FBgn0043836,
  • Tcp1-like,
  • FBan0005374

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7 Alleles

DB identifier Symbol Allele Class Organism
FBal0257323 T-cp1[HMS00639]   Drosophila melanogaster
FBal0181333 T-cp1[c01712]   Drosophila melanogaster
FBal0159695 T-cp1[c03987]   Drosophila melanogaster
FBal0262417 T-cp1[CPTI000037]   Drosophila melanogaster
FBal0208686 T-cp1[GD10468]   Drosophila melanogaster
FBal0222658 T-cp1[f01007]   Drosophila melanogaster
FBal0274648 T-cp1[NIG.5374R]   Drosophila melanogaster

147 Clones

Secondary Identifier DB identifier
CK01.33C.C11 FBcl0404738
CK01.12B.F1 FBcl0404784
569912 FBcl0404796
158931 FBcl0404821
120313 FBcl0404857
CK01.17B.D5 FBcl0404923
CK01.17B.G4 FBcl0404953
571318 FBcl0405007
AT24647 FBcl0030985
AT28572 FBcl0032969
bs21f11 FBcl0055081
CK00292 FBcl0060135
EN15854 FBcl0098805
EN02603 FBcl0098903
EN11501 FBcl0098939
GH10347 FBcl0118453
GH16080 FBcl0118597
GH25316 FBcl0118885
GH11383 FBcl0118903
GH08444 FBcl0119329
EK052912 FBcl0119618
EK193020 FBcl0119628
EK229947 FBcl0119632
EK261638 FBcl0119636
EK299939 FBcl0119648
EK257748 FBcl0119660
EK269645 FBcl0119690
EK239859 FBcl0119694
EK251721 FBcl0119720
EK159022 FBcl0119744

6 Exons

DB identifier Symbol
FBgn0003676:6 T-cp1:6
FBgn0003676:4 T-cp1:4
FBgn0003676:3 T-cp1:3
FBgn0003676:2 T-cp1:2
FBgn0003676:1 T-cp1:1
FBgn0003676:5 T-cp1:5

2 Transcripts

DB identifier Gene
FBtr0084290 T-cp1
FBtr0084291 T-cp1

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0084290-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0084291-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0084290-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0084291-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
42649 NCBI Entrez Gene identifiers FBgn0003676
67604 BioGRID FBgn0003676

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 4676.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 5144.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 3373.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 4245.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 4799.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 3145.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 3234.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 3704.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 3550.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 4310.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 3601.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 3079.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 3144.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 3705.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 4589.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 4682.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2826.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 3901.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 5819.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 3978.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 4581.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 5069.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 3726.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2633.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2729.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 5271.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1124.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 765.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1193.0
FBgn0003676 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1689.0

5 Introns

DB identifier
Organism . Name
intron_FBgn0003676:6_FBgn0003676:4 Drosophila melanogaster
intron_FBgn0003676:4_FBgn0003676:3 Drosophila melanogaster
intron_FBgn0003676:3_FBgn0003676:2 Drosophila melanogaster
intron_FBgn0003676:2_FBgn0003676:1 Drosophila melanogaster
intron_FBgn0003676:5_FBgn0003676:3 Drosophila melanogaster

21 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage T-cp1 none 0.029564829   19067489
Lipid storage T-cp1 none 0.244780586   19067489
Cell size and cell-cycle regulation (1) T-cp1 none sp   16496002
Candida albicans phagocytosis (1) T-cp1 Decreased Candida albicans phagocytosis np   16336044
Candida albicans phagocytosis (2) T-cp1 Decreased Escherichia coli phagocytosis 42   16336044
Candida albicans phagocytosis (3) T-cp1 Decreased latex beads phagocytosis 33   16336044
Combinatorial effect with methyl methanesulphonate (1) T-cp1 none sp   19543366
Combinatorial effect with methyl methanesulphonate (2) T-cp1 Synthetic lethal with methyl methanesulphonate sp   19543366
Muscle morphogenesis and function (1) T-cp1 Lethal np   20220848
Heat nociception (1) T-cp1 Developmentally lethal 0   21074052
Heart development and function (1) T-cp1 Embryonic lethal or no offspring 0   20371351
Serratia marcescens infection (1) T-cp1 none -0.409448818897637   19520911
Notch pathway regulation (4) T-cp1 Completely lethal (pupal) sp   19363474
Adiposity regulation (1) T-cp1 none -0.401   20074523
RTK-Ras-ERK pathway regulation (1) T-cp1 Increased ERK phosphorylation after EGF stimulation 3.03 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) T-cp1 none -0.75 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) T-cp1 none -0.57 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) T-cp1 none -0.14 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation T-cp1 none 0.78   23263283
Glycosylation regulation (1) T-cp1 none sp   21203496
Huntingtin (Htt) aggregates formation T-cp1 Decreased formation of mutant Huntingtin (Httex1-Qn) protein aggregates np   20100940

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