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Gene : l(2)35Df D. melanogaster

DB identifier  ? FBgn0001986 Secondary Identifier  ? CG4152
Name  ? lethal (2) 35Df Source  FlyBase
  • synonyms:
  • l(2)k14423,
  • l(2)br44,
  • l(2)35Df,
  • FBan0004152,
  • FBgn0027576,
  • CG4152,
  • BcDNA:GH07290,
  • FBgn0001986,
  • l.2.35Df,
  • FBgn0041116,
  • lethal(2)35Df,
  • l(2)k14422,
  • FBgn0027880,
  • br44,
  • BG:DS09217.2,
  • FBgn0032570

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12 Alleles

DB identifier Symbol Allele Class Organism
FBal0179162 l(2)35Df[c05313]   Drosophila melanogaster
FBal0065808 l(2)35Df[k14422]   Drosophila melanogaster
FBal0008531 l(2)35Df[k14423]   Drosophila melanogaster
FBal0008528 l(2)35Df[2]   Drosophila melanogaster
FBal0061318 l(2)35Df[HL58]   Drosophila melanogaster
FBal0008527 l(2)35Df[1]   Drosophila melanogaster
FBal0008529 l(2)35Df[3]   Drosophila melanogaster
FBal0008530 l(2)35Df[4]   Drosophila melanogaster
FBal0220079 l(2)35Df[G12516]   Drosophila melanogaster
FBal0209853 l(2)35Df[GD11229]   Drosophila melanogaster
FBal0230828 l(2)35Df[KK100563]   Drosophila melanogaster
FBal0274111 l(2)35Df[NIG.4152R]   Drosophila melanogaster

140 Clones

Secondary Identifier DB identifier
EP03616 FBcl0088031
EK173717 FBcl0102376
EK205663 FBcl0102390
EK259933 FBcl0102396
EK234631 FBcl0102616
GH07290 FBcl0122345
GM09051 FBcl0143370
LD20038 FBcl0157736
LD02559 FBcl0158105
LD12317 FBcl0158106
LD10786 FBcl0158107
LD12395 FBcl0158108
LD05183 FBcl0158109
LD27110 FBcl0172424
LD42823 FBcl0172426
LD38737 FBcl0172427
LD40261 FBcl0172428
LD28043 FBcl0172430
LD45310 FBcl0172431
LD41581 FBcl0172436
RE37157 FBcl0219517
RE13066 FBcl0219518
RE37842 FBcl0219530
RE19983 FBcl0219540
RE57712 FBcl0219544
RE74165 FBcl0219545
RE14886 FBcl0219548
RE23290 FBcl0219549
RE50675 FBcl0219551
RE48775 FBcl0219553

2 Exons

DB identifier Symbol
FBgn0001986:1 l(2)35Df:1
FBgn0001986:2 l(2)35Df:2

1 Transcripts

DB identifier Gene
FBtr0080760 l(2)35Df

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0080760-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080760-3-prime-utr Drosophila melanogaster

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0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
48782 NCBI Entrez Gene identifiers FBgn0001986
71682 BioGRID FBgn0001986

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 612.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 665.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 605.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 559.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 614.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 600.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 589.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 872.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 384.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 821.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 657.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 798.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 480.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 432.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 574.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 695.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 555.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 545.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 737.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 583.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 717.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 730.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 622.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 526.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 676.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1512.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1466.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1407.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 900.0
FBgn0001986 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 771.0

1 Introns

DB identifier
Organism . Name
intron_FBgn0001986:1_FBgn0001986:2 Drosophila melanogaster

32 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage l(2)35Df none -0.56195931   19067489
Lipid storage l(2)35Df none -0.691519933   19067489
Hedgehog signaling l(2)35Df Decreased Hedgehog reporter activity -2.17   16311596
Constitutive protein secretion and Golgi organization (1) l(2)35Df Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) l(2)35Df none sp   16496002
Cell size and cell-cycle regulation (1) l(2)35Df none sp   16496002
Candida albicans phagocytosis (1) l(2)35Df none np   16336044
Muscle morphogenesis and function (1) l(2)35Df Lethal np   20220848
Muscle morphogenesis and function (1) l(2)35Df Lethal np   20220848
Muscle morphogenesis and function (3) l(2)35Df Split myofibril, fading Z-line np   20220848
Heat nociception (1) l(2)35Df Developmentally lethal -1.17   21074052
Heat nociception (1) l(2)35Df Developmentally lethal -1.17   21074052
Heart development and function (1) l(2)35Df none 1   20371351
Serratia marcescens infection (1) l(2)35Df none 0   19520911
Notch pathway regulation (4) l(2)35Df Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) l(2)35Df Completely lethal (pupal) sp   19363474
Hh pathway regulation l(2)35Df Downregulation of Hh pathway -0.356050560390466   17903264
Hh pathway regulation l(2)35Df Downregulation of Hh pathway -0.31505555036416   17903264
Self-renewal and differentiation in neural stem cells l(2)35Df Neuroblast less large cells, ganglion mother cell larger cell size, ganglion mother cell shorter lineages, ganglion mother cell shape, neuroblast loss, neuroblast loss with unchanged neuroblast cell size, neuroblast underproliferation , lethal sp   21549331
Self-renewal and differentiation in neural stem cells l(2)35Df GFP aggregates number, GFP aggregates size, neuroblast smaller cell size, ganglion mother cell shorter lineages, neuroblasts smaller, neuroblast underproliferation, lethal sp   21549331
Adiposity regulation (1) l(2)35Df Decreased triglyceride expression -0.888   20074523
Adiposity regulation (2) l(2)35Df Decreased triglyceride expression -0.628   20074523
Adiposity regulation (3) l(2)35Df none 0.146   20074523
Adiposity regulation (4) l(2)35Df Lethal or developmental delay d/l   20074523
Adiposity regulation (5) l(2)35Df Lethal or developmental delay d/l   20074523
RTK-Ras-ERK pathway regulation (1) l(2)35Df none 0.34 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) l(2)35Df Decreased ERK phosphorylation after EGF stimulation -1.81 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) l(2)35Df none -0.06 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) l(2)35Df none 0.67 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation l(2)35Df none -0.43   23263283

0 Submissions