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Gene : Appl D. melanogaster

DB identifier  ? FBgn0000108 Secondary Identifier  ? CG7727
Name  ? beta amyloid protein precursor-like Source  FlyBase
  • synonyms:
  • FBgn0000108,
  • Abeta,
  • FBgn0028498,
  • Beta amyloid protein precursor-like,
  • BcDNA:GH04413,
  • CG7727,
  • FBan0007727,
  • APPL,
  • APP-like,
  • amyloid precursor protein,
  • Amyloid Precursor Protein-like,
  • beta-amyloid-protein-precursor-like,
  • APP,
  • EG:65F1.5,
  • Amyloid Precursor-Like Protein

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31 Alleles

DB identifier Symbol Allele Class Organism
FBal0268079 Appl[s.Scer\UAS.T:Ivir\HA1]   Drosophila melanogaster
FBal0268080 Appl[dAICD.Scer\UAS.T:Ivir\HA1]   Drosophila melanogaster
FBal0258380 Appl[G3.dsRNA.Scer\UAS]   Drosophila melanogaster
FBal0188193 Appl[f04460]   Drosophila melanogaster
FBal0188194 Appl[f03252]   Drosophila melanogaster
FBal0152781 Appl[BG00720]   Drosophila melanogaster
FBal0157348 Appl[BG02664]   Drosophila melanogaster
FBal0241475 Appl[sdDeltaE2.Scer\UAS]   Drosophila melanogaster
FBal0241476 Appl[sdDeltaE1.Scer\UAS]   Drosophila melanogaster
FBal0241477 Appl[sdDeltaNPTY.Scer\UAS]   Drosophila melanogaster
FBal0241478 Appl[sdDeltaIC.Scer\UAS]   Drosophila melanogaster
FBal0028991 Appl[hs.PL]   Drosophila melanogaster
FBal0033467 Appl[sd.hs]   Drosophila melanogaster
FBal0062165 Appl[s.hs]   Drosophila melanogaster
FBal0086921 Appl[s]   Drosophila melanogaster
FBal0086920 Appl[sd]   Drosophila melanogaster
FBal0028990 Appl[d] loss of function allele, amorphic allele - genetic evidence Drosophila melanogaster
FBal0240847 Appl[JF02878]   Drosophila melanogaster
FBal0103100 Appl[C100.Scer\UAS]   Drosophila melanogaster
FBal0188195 Appl[dsRNA.Scer\UAS]   Drosophila melanogaster
FBal0103099 Appl[s.Scer\UAS]   Drosophila melanogaster
FBal0097416 Appl[Scer\UAS.cTa]   Drosophila melanogaster
FBal0103096 Appl[sdDeltaCg.Scer\UAS]   Drosophila melanogaster
FBal0103093 Appl[sd.Scer\UAS]   Drosophila melanogaster
FBal0198740 Appl[GD3170]   Drosophila melanogaster
FBal0279045 Appl[HMS01931]   Drosophila melanogaster
FBal0221084 Appl[hs.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0221085 Appl[Scer\UAS.T:Ivir\HA1]   Drosophila melanogaster
FBal0221088 Appl[Scer\UAS.cCSa]   Drosophila melanogaster
FBal0221089 Appl[Abeta.Scer\UAS.T:Ivir\HA1]   Drosophila melanogaster

101 Clones

Secondary Identifier DB identifier
DPiM_GH04413 FBcl0740747
Nfly-115 FBcl0006407
EK302235 FBcl0008342
EK098818 FBcl0008388
EK266032 FBcl0008484
EK169053 FBcl0008506
EK050126 FBcl0008564
EK302060 FBcl0008584
EK265103 FBcl0008658
EK063457 FBcl0012616
EK306549 FBcl0012632
EK152409 FBcl0012710
EK261909 FBcl0012730
EK011706 FBcl0012754
EK267623 FBcl0012776
EK305906 FBcl0012818
EK097023 FBcl0012838
EK044321 FBcl0012900
EK046048 FBcl0012924
EK060009 FBcl0012946
EK290550 FBcl0012970
EK091842 FBcl0012988
EK207547 FBcl0013088
EK139441 FBcl0013104
EK131263 FBcl0013124
EK291501 FBcl0013144
EK128630 FBcl0013186
EK223001 FBcl0013210
EK086435 FBcl0013232
EK134158 FBcl0013256

20 Exons

DB identifier Symbol
FBgn0000108:1 Appl:1
FBgn0000108:3 Appl:3
FBgn0000108:4 Appl:4
FBgn0000108:5 Appl:5
FBgn0000108:6 Appl:6
FBgn0000108:8 Appl:8
FBgn0000108:10 Appl:10
FBgn0000108:12 Appl:12
FBgn0000108:14 Appl:14
FBgn0000108:15 Appl:15
FBgn0000108:17 Appl:17
FBgn0000108:19 Appl:19
FBgn0000108:7 Appl:7
FBgn0000108:11 Appl:11
FBgn0000108:20 Appl:20
FBgn0000108:9 Appl:9
FBgn0000108:13 Appl:13
FBgn0000108:2 Appl:2
FBgn0000108:16 Appl:16
FBgn0000108:18 Appl:18

6 Transcripts

DB identifier Gene
FBtr0070109 Appl
FBtr0307292 Appl
FBtr0307295 Appl
FBtr0307293 Appl
FBtr0307294 Appl
FBtr0307291 Appl

12 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0070109-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0307291-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0307292-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0307293-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0307294-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0307295-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0070109-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0307291-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0307292-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0307293-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0307294-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0307295-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
31002 NCBI Entrez Gene identifiers FBgn0000108
57571 BioGRID FBgn0000108

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 221.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 305.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 194.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 556.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 246.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 182.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 307.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 231.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 478.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 285.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 294.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 110.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 444.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 291.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 296.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 132.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 276.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 161.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 325.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 278.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 474.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 249.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 291.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 312.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 375.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 260.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 207.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 391.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 196.0
FBgn0000108 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 565.0

27 Introns

DB identifier
Organism . Name
intron_FBgn0000108:1_FBgn0000108:3 Drosophila melanogaster
intron_FBgn0000108:3_FBgn0000108:4 Drosophila melanogaster
intron_FBgn0000108:4_FBgn0000108:5 Drosophila melanogaster
intron_FBgn0000108:5_FBgn0000108:7 Drosophila melanogaster
intron_FBgn0000108:7_FBgn0000108:9 Drosophila melanogaster
intron_FBgn0000108:9_FBgn0000108:11 Drosophila melanogaster
intron_FBgn0000108:11_FBgn0000108:12 Drosophila melanogaster
intron_FBgn0000108:12_FBgn0000108:14 Drosophila melanogaster
intron_FBgn0000108:14_FBgn0000108:15 Drosophila melanogaster
intron_FBgn0000108:15_FBgn0000108:17 Drosophila melanogaster
intron_FBgn0000108:17_FBgn0000108:19 Drosophila melanogaster
intron_FBgn0000108:3_FBgn0000108:5 Drosophila melanogaster
intron_FBgn0000108:2_FBgn0000108:3 Drosophila melanogaster
intron_FBgn0000108:14_FBgn0000108:16 Drosophila melanogaster
intron_FBgn0000108:16_FBgn0000108:18 Drosophila melanogaster
intron_FBgn0000108:18_FBgn0000108:20 Drosophila melanogaster
intron_FBgn0000108:5_FBgn0000108:6 Drosophila melanogaster
intron_FBgn0000108:6_FBgn0000108:9 Drosophila melanogaster
intron_FBgn0000108:9_FBgn0000108:10 Drosophila melanogaster
intron_FBgn0000108:10_FBgn0000108:13 Drosophila melanogaster
intron_FBgn0000108:13_FBgn0000108:14 Drosophila melanogaster
intron_FBgn0000108:7_FBgn0000108:8 Drosophila melanogaster
intron_FBgn0000108:8_FBgn0000108:11 Drosophila melanogaster
intron_FBgn0000108:17_FBgn0000108:20 Drosophila melanogaster
intron_FBgn0000108:6_FBgn0000108:8 Drosophila melanogaster
intron_FBgn0000108:8_FBgn0000108:10 Drosophila melanogaster
intron_FBgn0000108:10_FBgn0000108:12 Drosophila melanogaster

16 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Appl none -1.149040409   19067489
Cell size and cell-cycle regulation (1) Appl none sp   16496002
Cell size and cell-cycle regulation (1) Appl none sp   16496002
Muscle morphogenesis and function (1) Appl none np   20220848
Muscle morphogenesis and function (1) Appl none np   20220848
Muscle morphogenesis and function (1) Appl none np   20220848
Heat nociception (1) Appl none -0.4   21074052
Heart development and function (1) Appl none 1   20371351
Serratia marcescens infection (1) Appl none 0.939393939393939   19520911
Notch pathway regulation (4) Appl none 0   19363474
Notch pathway regulation (4) Appl none 0   19363474
PGN-induced dJNK phosphorylation Appl Increased P-JNK protein expression with PGN 3.01 15 min PGN induction 19893628
Adiposity regulation (1) Appl none -0.263   20074523
Hippo pathway regulation Appl none -2.07   23263283
Muscle development and maintenance Appl Climbing defect sp  
Muscle maintenance Appl none sp  

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