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Encyclopedia of C. elegans 3%27UTRs and their regulatory elements - Illumina sequencing of RACE pools

experiment: Encyclopedia of C. elegans 3%27UTRs and their regulatory elements - Illumina sequencing of RACE pools project: The 3' UTRome PI: Fabio Piano Labs: Fabio Piano
The 3' untranslated region (3'UTR) constitutes a major site of post-transcriptional regulation of gene expression. Sequence elements in the 3'UTR interact with trans-acting regulators such as microRNAs that affect translation and stability. The overall aim is to use a 3'RACE cloning-sequencing stragety to identify the 3'UTRs of C. elegans transcripts and explore their heterogeneity in different developmental stages and tissues.