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experiment: Chromatin ChIP-seq of non-Histone Chromosomal Proteins in C. elegans | project: Chromatin Function | PI: Jason Lieb | Labs: Abby Dernburg, Arshad Desai, Jason Lieb, Julie Ahringer, Susan Strome |
The focus of our analysis will be elements that specify nucleosome positioning and occupancy, control domains of gene expression, induce repression of the X chromosome, guide mitotic segregation and genome duplication, govern homolog pairing and recombination during meiosis, and organize chromosome positioning within the nucleus. Our 126 strategically selected targets include RNA polymerase II isoforms, dosage-compensation proteins, centromere components, homolog-pairing facilitators, recombination markers, and nuclear-envelope constituents. We will integrate information generated with existing knowledge on the biology of the targets and perform ChIP-seq analysis on mutant and RNAi extracts lacking selected target proteins. |
All features generated by this experiment:
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All entries in public repositories generated by this experiment |