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Changes in expression of small RNAs during aging in C. elegans

experiment: Changes in expression of small RNAs during aging in C. elegans project: The C. elegans Transcriptome PI: Robert Waterston Labs: Frank Slack
We report a significant number of miRNAs and other non-coding small RNAs show dramatic changes in expression during aging in C. elegans. RNAs were prepared from four diffrent timepoints during adulthood of C. elegans hermaphrodites, Day 0, 5, 8 and 12 post-L4 molt, and used for making cDNA libraries for small RNAs. Each library was sequenced using recent advances in high-throughput sequencing technology, Solexa. This study should lead to a better understanding of the aging process and age-related diseases.

NO FEATURES GENERATED BY THIS EXPERIMENT All GBrowse tracks generated for this experiment:
GBrowse tracks: by chromosome
All 8 tracks I II III IV V X
All entries in public repositories generated by this experiment
There are 4 RNA-seq submissions for this experiment:
DCC id Name developmental stage days post-L4 strain temperature Embargoed until Features, GBrowse and Data Files
modENCODE_6505


Related to: modENCODE_5383

Ce Day8 spe-9 23dC smallRNA RNA-seq Adult spe-9(hc88) 23dC 8 days post-L4 molt [ALL]
8 days [ALL]
BA671 [ALL]
23 degree celsius [ALL]
embargo expired
GBrowse tracks: YA_spe9day8_merged_ws220.soap.sam.bam.sorted
YA_spe9day8_merged_ws220.soap.sam.bam.sorted
GEO: GSM463027
GEO: GSM463030
SRA: SRR032281
SRA: SRR032284


4 files Download data files
modENCODE_6506


Related to: modENCODE_5384

Ce Day12 spe-9 23dC smallRNA RNA-seq Adult 23dC 12 days post-L4 stage larvae [ALL]
12 days [ALL]
BA671 [ALL]
23 degree celsius [ALL]
embargo expired
GBrowse tracks: YA_spe9day212_s_5.S3_ws220.soap.sam_sorted
YA_spe9day212_s_5.S3_ws220.soap.sam_sorted
GEO: GSM463028
SRA: SRR032282


2 files Download data files
modENCODE_6503


Related to: modENCODE_5381

Ce Day0 spe-9 23dC smallRNA RNA-seq young adult (23dC DAY0 post-L4 molt) [ALL]
BA671 [ALL]
23 degree celsius [ALL]
embargo expired
GBrowse tracks: YA_spe9day0_merged_ws220.soap.sam.bam.sorted
YA_spe9day0_merged_ws220.soap.sam.bam.sorted
GEO: GSM463025
GEO: GSM463029
SRA: SRR032279
SRA: SRR032283


4 files Download data files
modENCODE_6504


Related to: modENCODE_5382

Ce Day5 spe-9 23dC smallRNA RNA-seq Adult 23dC 5 days post-L4 stage larvae [ALL]
5 days [ALL]
BA671 [ALL]
23 degree celsius [ALL]
embargo expired
GBrowse tracks: YA_spe9day5_s_2.S3_ws220.soap.sam.bam.sorted
YA_spe9day5_s_2.S3_ws220.soap.sam.bam.sorted
GEO: GSM463026
SRA: SRR032280


2 files Download data files